Antiviral Activity of Some Plants Used in Nepalese Traditional Medicine

Research Center for Applied Science and Technology, Tribhuvan University, Kathmandu, Nepal.
Evidence-based Complementary and Alternative Medicine (Impact Factor: 1.88). 11/2007; 6(4):517-22. DOI: 10.1093/ecam/nem156
Source: PubMed


Methanolic extracts of 41 plant species belonging to 27 families used in the traditional medicine in Nepal have been investigated for in vitro antiviral activity against Herpes simplex virus type 1 (HSV-1) and influenza virus A by dye uptake assay in the systems HSV-1/Vero cells and influenza virus A/MDCK cells. The extracts of Astilbe rivularis, Bergenia ciliata, Cassiope fastigiata and Thymus linearis showed potent anti-herpes viral activity. The extracts of Allium oreoprasum, Androsace strigilosa, Asparagus filicinus, Astilbe rivularis, Bergenia ciliata and Verbascum thapsus exhibited strong anti-influenza viral activity. Only the extracts of A. rivularis and B. ciliata demonstrated remarkable activity against both viruses.

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Available from: Mohan Gewali, Mar 27, 2014
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    • "On the other hand, combination of adamantanamine glucuronide and the lyophilized flower infusion of V. thapsiforme exerted a discernible effect against influenza virus in chicken embryo Fig. 14 Other compounds isolated from Verbascum spp fibroblast cell cultures (Serkedjieva 2000). In connection with these data, the methanolic extract of V. thapsus from Nepal was revealed to have a robust antiinfluenza effect (Rajbhandari et al. 2009). "
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    • "Investigation was for in vitro antiviral activity against Herpes simplex virus type 1 (HSV-1) and influenza virus A by dye uptake assay systems HSV-1/Vero in the cells and influenza virus A/MDCK cells.V. thapsus exhibited strong anti-influenza virus activity with IC 50 < 6.25 mg/ml (Rajbhandari et al., 2009). "
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