Article

[Heart failure in men and women: important differences in the diagnostic workup and treatment].

Afd. Cardiologie, Erasmus MC-Centrum, Postbus 2040, 3000 CA Rotterdam.
Nederlands tijdschrift voor geneeskunde 11/2008; 152(40):2182-5. pp.2182-5
Source: PubMed

ABSTRACT To determine gender differences in diagnostic workup and treatment of patients with heart failure.
Retrospective.
The data of 8914 patients (of whom 4166 women; 47%) with confirmed heart failure, who participated in the Euro Heart Survey on Heart Failure (EHS-HF) were analysed.
On average, the women in the study were older than the men (75 versus 68 years) and less often suffered from a coronary heart disease (56 versus 66%). Women were more likely to have hypertension (59 versus 49%), diabetes mellitus (29 versus 26%), or valvular heart disease (42 versus 36%). Fewer women had an ultrasonographic evaluation of ventricular function (59 versus 74%) and, among those investigated, fewer had left ventricular systolic dysfunction (44 versus 72%). These observed results remained stable after adjustment for age and other possible confounding variables. Medication with a documented positive impact on survival, i.e. angiotensin converting enzyme (ACE) inhibitors, beta-blocking drugs and the diuretic spironolactone, was prescribed less often to women than men. Women, however, received symptomatic medication such as other diuretics and digoxin more often than men.
Men and women with heart failure differed with respect to a number of relevant clinical characteristics. Clinicians should take good note of this and take measures to prevent differences in patient care.

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Keywords

beta-blocking drugs
 
Clinicians
 
coronary heart disease
 
diuretic spironolactone
 
documented positive impact
 
EHS-HF
 
Euro Heart Survey
 
gender differences
 
good note
 
heart failure
 
Men
 
observed results
 
patient care
 
patients
 
relevant clinical characteristics
 
ultrasonographic evaluation
 
valvular heart disease
 
variables
 
ventricular systolic dysfunction
 
Women