Functionalizing Genomic Data for Personalization of Medicine

The Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, USA.
Clinical Pharmacology &#38 Therapeutics (Impact Factor: 7.9). 11/2012; 93(4). DOI: 10.1038/clpt.2012.219
Source: PubMed


The wealth of genomic information currently available to researchers and clinicians has dramatically changed the way some diseases are defined. However, leveraging this information is a major challenge, in part because previously established concepts and tools used for research and development are largely inadequate. Using the example of cancer genomics, this article focuses on systems-biology approaches to inform the development of personalized medicine.Clinical Pharmacology & Therapeutics (2013); 93 4, 309-311. doi:10.1038/clpt.2012.219

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