Ossifying renal tumor of infancy
Department of Paediatric Urology, University of Regensburg, Klinik St. Hedwig, Steinmetzstrasse 1-3, 93049 Regensburg, Germany.Journal of pediatric urology (Impact Factor: 0.9). 07/2007; 3(3):258-61. DOI: 10.1016/j.jpurol.2006.05.009
A renal ossifying tumor of infancy is a rare event with few cases having been published, and the etiology has not yet been established. We report on two new cases of this unusual neoplasm. A 2-year-old boy presented with intermittent painless gross hematuria. After several diagnostic procedures, an open pyelolithotomy was performed and the histological diagnosis of renal tumor of infancy was finally made. The history of the second case is very similar. An 8-week-old infant presented with gross hematuria. As in the first case, an open pyelolithotomy was performed and a tumor entirely covered with blood clots was found in the renal pelvis and completely removed. A histological diagnosis of renal ossifying tumor of infancy was made. Using the literature available, the histological criteria and biological behavior are discussed, together with the diagnostic and therapeutic algorithm for this tumor. In infants with gross hematuria and a calcified (non-)invasive mass in the pelvi-calceal system, renal ossifying tumor should be considered in the differential diagnosis. MRI or CT scan offers a good diagnostic guide.
- Klinische Pädiatrie 05/2011; 223(3):178-9. DOI:10.1055/s-0031-1275350 · 1.06 Impact Factor
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ABSTRACT: We present the case of a 6-month-old boy who was referred to us with the chief complaint of intermittent painless gross hematuria. Computed tomography (CT) scan of the abdomen showed a partially calcified soft-tissue mass that was located in the lower pole of the right kidney and extended into the collecting system. Consequently, a partial nephrectomy was performed. The resected specimen showed that the tumor was partially calcified and occupied the renal pelvis. The histological findings suggested a diagnosis of ossifying renal tumor of infancy (ORTI), only 16 cases of which have been reported in the literature. The pathogenesis of this condition has not been well established. ORTI should be considered in the differential diagnosis for infants with gross hematuria and a calcified mass in the pelvicalyceal system.Journal of Pediatric Surgery 02/2013; 48(2):e37-40. DOI:10.1016/j.jpedsurg.2012.12.020 · 1.39 Impact Factor
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ABSTRACT: A 4-month-old boy presented with persistent gross hematuria. At ultrasonography, a 3.5-cm echogenic mass with posterior shadowing and tumor vascularity was detected within the right renal pelvis. Precontrast CT showed a slightly hyperattenuating mass in the renal pelvis. At MRI the mass was heterogeneously hypointense on T2-weighted images and isointense on T1-weighted images. Contrast-enhanced CT and MRI both revealed peripheral enhancement of the mass. A histological diagnosis of ossifying renal tumor of infancy was made after open pyelostomy and tumor enucleation. We suggest that ossifying renal tumor of infancy should be considered when a mass with posterior acoustic shadowing and tumor vascularity on US, hyperattenuation on precontrast CT and hypointensity on T2-weighted MRI is seen within the renal pelvis of an infant with hematuria.Pediatric Radiology 01/2014; 44(5). DOI:10.1007/s00247-013-2855-2 · 1.57 Impact Factor
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