Acute myocardial infarctions, strokes and influenza: seasonal and pandemic effects

Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, USA.
Epidemiology and Infection (Impact Factor: 2.49). 01/2013; 141(04):735-744. DOI: 10.1017/S0950268812002890
Source: PubMed

ABSTRACT SUMMARY The incidence of myocardial infarctions and influenza follow similar seasonal patterns. To determine if acute myocardial infarctions (AMIs) and ischaemic strokes are associated with influenza activity, we built time-series models using data from the Nationwide Inpatient Sample. In these models, we used influenza activity to predict the incidence of AMI and ischaemic stroke. We fitted national models as well as models based on four geographical regions and five age groups. Across all models, we found consistent significant associations between AMIs and influenza activity, but not between ischaemic strokes and influenza. Associations between influenza and AMI increased with age, were greatest in those aged >80 years, and were present in all geographical regions. In addition, the natural experiment provided by the second wave of the influenza pandemic in 2009 provided further evidence of the relationship between influenza and AMI, because both series peaked in the same non-winter month.

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    ABSTRACT: BACKGROUNDSeasonal variation in admissions and mortality due to acute myocardial infarction has been observed in different countries. Since there are scarce reports about this variation in Iran, this study was carried out to determine the existence of seasonal rhythms in hospital admissions for acute myocardial infarction, and in mortality due to acute myocardial infarction (AMI) in elderly patients in Isfahan city.METHODSThis prospective hospital-based study included a total of 3990 consecutive patients with acute myocardial infarction admitted to 13 hospitals from January 2002 to December 2007. Seasonal variations were analyzed with the Kaplan-Meier table, log rank test, and Cox regression model.RESULTSThere was a statistically significant relationship between the occurrence of heart disease based on season and type of acute myocardial infarction anatomical (P < 0.001). The relationship between the occurrence of death and season and type of AMI according to International Classification of Diseases code 10 (ICD) was also observed and it was statistically significant (P = 0.026). Hazard ratio for death from acute myocardial infarction were 0.96 [Confidence interval of 95% (95% CI) = 0.78-1.18], 0.9 (95%CI = 0.73-1.11), and 1.04 (95%CI = 0.85-1.26) during spring, summer, and winter, respectively.CONCLUSIONThere is seasonal variation in hospital admission and mortality due to AMI; however, after adjusting in the model only gender and age were significant predictor factors.
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    ABSTRACT: Interwar Poland in the European context divorced great attention to the history of medicine and philosophy. Significant Medical History and Philosophy school took its part in Vilnius. Professor Stanislaw Trzebiński, a head of Vilnius Medical History and Philosophy school, investigated the development of Vilnius medicine in XVI-XIX centuries, constantly edited by a leading journal in the field of medical history and philosophy “The Archives for a Medical History and Philosophy as well as Nature history”. The medical history, medical logic, propedeutics, medical ethics were being taught in Stephen Bathory university Medical faculty. The aim of this paper is to make a short overview of the History of Medicine and Philosophy Department in the year 1922-1939. The activities and the most important achievements of the department will be reviewed in this review article. Correspondence to:
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    ABSTRACT: Hurricane Sandy made landfall in New Jersey (NJ) on October 29, 2012. We studied the impact of this extreme weather event on the incidence of, and 30-day mortality from, cardiovascular (CV) events (CVEs), including myocardial infarctions (MI) and strokes, in NJ. Data were obtained from the MI data acquisition system (MIDAS), a database of all inpatient hospital discharges with CV diagnoses in NJ, including death certificates. Patients were grouped by their county of residence, and each county was categorized as either high- (41.5% of the NJ population) or low-impact area based on data from the Federal Emergency Management Agency and other sources. We utilized Poisson regression comparing the 2 weeks following Sandy landfall with the same weeks from the 5 previous years. In addition, we used CVE data from the 2 weeks previous in each year as to adjust for yearly changes. In the high-impact area, MI incidence increased by 22%, compared to previous years (attributable rate ratio [ARR], 1.22; 95% confidence interval [CI], 1.16, 1.28), with a 31% increase in 30-day mortality (ARR, 1.31; 95% CI, 1.22, 1.41). The incidence of stroke increased by 7% (ARR, 1.07; 95% CI, 1.03, 1.11), with no significant change in 30-day stroke mortality. There were no changes in incidence or 30-day mortality of MI or stroke in the low-impact area. In the 2 weeks following Hurricane Sandy, there were increases in the incidence of, and 30-day mortality from, MI and in the incidence of stroke. © 2014 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.
    Journal of the American Heart Association 10/2014; 3(6). DOI:10.1161/JAHA.114.001354 · 2.88 Impact Factor


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May 29, 2014