Article

Potential Functions of Lemon Grass (Cymbopogon citratus) in Health and Disease

International Journal of Pharmaceutical & Biological Archives 0976 – 3333 01/2012; 2012; 3(5):1035-1043.

ABSTRACT Plants are utilized as therapeutic agents since time immemorial in both organized (Ayurveda, Unani) and unorganized (folk, tribal, native) form. Plants have been identified as the potent therapeutic agent, due to the presence of nutritional (minerals and vitamins) and non-nutritional (fibres, active phytochemicals, including the flavonoids, terpenoids, lignans, sulfides, polyphenolics, carotenoids, coumarins, saponins, plant sterols, curcumins, and phthalides) component, hence promoted as "functional food". The present paper highlights the functional properties of Lemon grass (Cymbopogon citratus), which has been consumed in various forms such in Thai, Vietnamese and South East Asian cuisines. It is a highly rated folk medicine in Brazil and have been associated with health claims such as treatment in coughs, constipation, elephantiasis flu, gingivitis, headache leprosy, malaria, ophthalmia, pneumonia, vascular disorders, diarrhoea and stomach ache. It has been claimed to be anti-inflammatory, vasorelaxing, diuretic, remedy in treating ringworm infestation, for nervous, gastrointestinal disturbances, fevers and hypertension. Lemon grass has high antioxidant levels. However, though it has obtained a GRAS status, clinical trials on humans are warranted. INTRODUCTION Lemon grass Cymbopogon citratus is an aromatic perennial tall grass with rhizomes and densely tufted fibrous root. It has short underground stems with ringed segments, coarse, green slightly leathery leaves in dense clusters (Carlin, et al., 1986). The plant is a native herb from India and is cultivated in other tropical and subtropical countries. (Figueirinha et al 2008). The Botanical classification of lemon grass is presented in (Table 1). Several species of lemon grass such as Cymbopogon bombycinus , Cymbopogon ambiguus , Cymbopogon obtectus , Cymbopogon refractus, Cymbopogon citrate, Cymbopogon nardus, Cymbopogon schoenanthus etc found in countries such as Australia, China, India, Africa and others (Table 2). There are several varieties of lemon grass available in the market ranging from Sugnadhi OD 19 to CKP 25 as seen in (Table 3). Agro-climatic Requirements The crop grows well in both tropical and subtropical climates at an elevation up to 900 m. However, ideal conditions for growing lemon

2 Bookmarks
 · 
792 Views
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The hypoglycemic effects of water and butanolic extracts prepared from leaves of Cecropia obtusifolia (Cecropiaceae) were examined in streptozotocin induced diabetic rats. A single oral administration of a water extract at doses of 90 and 150 mg/kg and of a butanol extract at doses of 9 and 15 mg/kg significantly (P<0.05) lowered the plasma glucose levels in diabetic rats after 3 h administration. Glibenclamide was used as reference and showed similar hypoglycemic effect to the tested extracts at a dose of 3 mg/kg. The flavone, isoorientin and 3-caffeoylquinic acid (chlorogenic acid), were isolated as the important constituents of the plant and were identified as the main constituents in both extracts, too.
    Journal of Ethnopharmacology 12/2001; 78(2-3):145-9. · 2.76 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Cymbopogon citratus was analyzed for its chemical constituents. Proximate analysis revealed that the sample contained moisture content: 5.76%; crude protein 4.56%, ash content: 20.00%, crude fat 5.10%, Carbohydrate 55.00% and crude fibre: 9:28. The food energy of the sample was 360.55 cal/100g. The phytochemical analysis of the ethanolic extracts of cymbopogon citratus indicates that it has alkaloids, saponins tannins, anthraquinones, steroids, phenols and flavonoids. Test for antibacterial activity using agar diffusion technique shows that antibacterial activity was active on S. typhi with Minimum Inhibitory Concentration (MIC) of 50 mg/ml but inactive on E. coli , L. monocytogenes and S. aureus .
    Pakistan Journal of Nutrition. 01/2009;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Leaves from cultivated Cymbopogon citratus were extracted with methanol, 80% aqueous ethanol and water (infusion and decoction) and the extracts were assessed for their antiradical capacity by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay; the infusion extract exhibited the strongest activity. Tannins, phenolic acids (caffeic and p-coumaric acid derivatives) and flavone glycosides (apigenin and luteolin derivatives) were identified in three different fractions obtained from an essential oil-free infusion, and a correlation with their scavenger capacity for reactive oxygen species was studied. The tannin and flavonoid fractions were the most active against species involved in oxidative damage processes. In the flavonoid fraction, representing 6.1% of the extract, thirteen compounds (O- and C-glycosylflavones) were tentatively identified by high performance liquid chromatography, coupled to photodiode-array and electrospray ionization mass spectrometry detectors (HPLC–PDA–ESI/MS), nine of which were identified for the first time in this plant, all of them being C-glycosylflavones (mono-C-, di-C- and O,C-diglycosylflavones). The potential beneficial and protective value of the identified polyphenols for human health is discussed.
    Food Chemistry - FOOD CHEM. 01/2008; 110(3):718-728.

Full-text

View
6,662 Downloads
Available from
Jun 2, 2014