Pharmaceutical and Herbal Products That May Contribute to Dry Eyes
ABSTRACT : Symptomatic dryness of the eyes is a most common blepharoplasty complication. The authors reviewed the medications and herbal products that may potentiate this complication.
: The MEDLINE and PubMed databases were searched for the years 1991 to 2011. Search terms included "dry eye syndrome," "keratitis sicca," "keratoconjunctivitis sicca," "ocular side effects," "herbal supplements," "herbals and dry eye," "dry eye risk factors," "etiology of dry eye," "drugs side effects," "drugs and dry eye," "dietary supplements," "ocular toxicity," and "tear film." References from herbal product reviews and eligible medication reports were searched for additional articles. A manual search was also conducted based on citations in the published literature.
: Of 232 articles found to be related to dry eye syndrome and possible risk factors, 196 were excluded because they did not discuss medications or herbal products as risk factors in dry eye syndrome. Thirty-six articles that examined the pathophysiology and risk factors of dry eye were included. Nine books were reviewed that contained some information regarding the association of medications and herbal products with dry eye. These agents were then categorized based on mechanism of action and usage. Medications listed include antihistamines, decongestants, antidepressants, anticonvulsants, antipsychotics, antiparkinson drugs, beta-blockers, and hormone replacement therapy. The three main herbal products that contribute to dry eye are niacin, echinacea, and kava. There was a strong association between anticholinergic alkaloids and dry eye.
: This study identifies the medications and herbal products that should be considered when a patient undergoes blepharoplasty and complains of symptoms associated with dryness of the eyes.
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ABSTRACT: Aesthetic eyelid surgery involves intricate techniques to improve the appearance of the periorbital region. In the presence of preoperative ptosis, lower lid laxity or malposition, prominent eyes, and xerophthalmia (dry eyes), patients are at an increased risk of developing postoperative complications such as scleral show, ectropion, corneal injury, and persistent ptosis. The authors identify patients at increased risk for functional problems after blepharoplasty and describe detailed preoperative evaluation to identify patients who may be at increased risk prior to surgery. In order to minimize the complications rates associated with blepharoplasty, it is of paramount importance to appreciate and address these functional concerns in the approach to blepharoplasty surgery. After reading this article, the participant should be able to demonstrate a systematic approach to identify high-risk blepharoplasty patients and manage functional issues in both upper and lower blepharoplasty.Plastic & Reconstructive Surgery 12/2014; 134(6):1154-70. DOI:10.1097/PRS.0000000000000748 · 3.33 Impact Factor
Investigative ophthalmology & visual science 09/2013; 55(9). DOI:10.1167/iovs.13-13166 · 3.66 Impact Factor