Genomewide association studies and common disease—realizing clinical utility

Weatherall Institute of Medicine, University of Oxford, Oxford, United Kingdom.
New England Journal of Medicine (Impact Factor: 54.42). 12/2012; 367(25):2370-1. DOI: 10.1056/NEJMp1212285
Source: PubMed
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    • "Consequently, for common diseases, individual variants have little diagnostic value (Fugger et al., 2012). To date, even combining results from many variants has provided limited value because only a proportion of causative loci have been identified and there are substantial environmental effects that contribute to most common diseases. "
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