The 2012 Nobel Prize in physiology or medicine: democratizing pluripotency for lung researchers
The Pulmonary Center and Center for Regenerative Medicine (CReM), Boston University and Boston Medical Center, 72 East Concord Street, R-304, Boston, MA 02118. .American Journal of Respiratory and Critical Care Medicine (Impact Factor: 13). 12/2012; 186(11):1080-1. DOI: 10.1164/rccm.201210-1857OE
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ABSTRACT: A conference, "Stem Cells and Cell Therapies in Lung Biology and Lung Diseases", was held July 25-28, 2011 at the University of Vermont, to review the current understanding of the role of stem and progenitor cells in lung repair after injury and to review the current status of cell therapy and ex vivo bioengineering approaches for lung diseases. These are rapidly expanding areas of study that both provide further insight into and challenge traditional views of mechanisms of lung repair after injury and pathogenesis of several lung diseases. The goals of the conference were to summarize the current state of the field, discuss and debate current controversies, and to identify future research directions and opportunities for both basic and translational research in cell based therapies for lung diseases. The goal of this article, which accompanies the formal conference report, is to provide a comprehensive review of the published literature in lung regenerative medicine from the last conference report through December 2012.Annals of the American Thoracic Society 07/2013; 10(5). DOI:10.1513/AnnalsATS.201304-090AW
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