Article

Reproducibility of Linear Array for Human Papillomavirus Genotyping

Division of Cancer Epidemiology and Genetics, NCI/NIH/DHHS, Bethesda, MD, United States.
Journal of clinical microbiology (Impact Factor: 4.23). 11/2012; 51(2). DOI: 10.1128/JCM.03036-12
Source: PubMed

ABSTRACT We conducted a Linear Array® test/re-test analysis using cytologic specimens from 198 women. 67.2% of samples had the same HPV types detected in both tests [type-specific positive agreement 83.3% overall (Kappa=0.9), 86.8% for carcinogenic types (Kappa=0.92)]. Discordance was highest with low hybridization signal strength. Overall, Linear Array was highly reproducible.

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