Engineering Natural Materials as Surface-Enhanced Raman Spectroscopy Substrates for In situ Molecular Sensing
ABSTRACT Surface-enhanced Raman spectroscopy (SERS) is a powerful analytical tool. However, its applications for in situ detection of target molecules presented on diverse material surfaces have been hindered by difficulties in rapid fabricating SERS-active substrates on the surfaces of these materials through a simple, low-cost, and portable approach. Here, we demonstrate our attempt to address this issue by developing a facile and versatile method capable of in situ generating silver nanoparticle film (SNF) on the hydrophobic (even superhydrophobic) or hydrophilic surfaces of natural materials in a simple, cheap, practical, and disposable manner. Taking advantage of the high SERS enhancement ability of the prepared SNF, the proposed strategy can be used for in situ inspecting herbicide and pesticide residues on vegetables, as well as the abuse of antiseptic in aquaculture industry. Therefore, it opens new avenues for advancing the application prospects of SERS technique in the fields of food safety, drug security, as well as environment monitoring.
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ABSTRACT: We prepare three-dimensional Cu plasmonic structures via a reduction of CuO photonic crystals replicated from butterfly wing scales. These Cu superstructures with high purity provide surface-enhanced Raman scattering (SERS) substrates for the label-free detection of DNA bases down to a micromolar level, which is achieved for the first time on Cu and even comparable to the detection-sensitivity for DNA bases on some Ag substrates. The generation of such superstructures has provided a substantial step for the bio-templated SERS substrates with high sensitivity, high reproducibility, and ultra-low cost to detect biomolecules, and presented affordable high-quality routine SERS consumables for corresponding bio-laboratories.ACS Applied Materials & Interfaces 09/2013; 5(20). DOI:10.1021/am402699c · 5.90 Impact Factor
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ABSTRACT: Ag nanostructures with surface-enhanced Raman scattering (SERS) activities have been fabricated by applying laser-direct writing (LDW) technique on silver oxide (AgO<sub>x</sub>) thin films. By controlling the laser powers, multi-level Raman imaging of organic molecules adsorbed on the nanostructures has been observed. This phenomenon is further investigated by atomic-force microscopy and electromagnetic calculation. The SERS-active nanostructure is also fabricated on transparent and flexible substrate to demonstrate our promising strategy for the development of novel and low-cost sensing chip.Optics Express 10/2013; 21(21):24460-7. DOI:10.1364/OE.21.024460 · 3.53 Impact Factor
- Comprehensive Reviews in Food Science and Food Safety 05/2014; 13(3). DOI:10.1111/1541-4337.12062 · 3.54 Impact Factor