Adverse effects of homeopathy: a systematic review of published case reports and case series

Complementary Medicine, Peninsula Medical School, Exeter, UK.
International Journal of Clinical Practice (Impact Factor: 2.54). 12/2012; 66(12):1178-88. DOI: 10.1111/ijcp.12026
Source: PubMed

ABSTRACT Aim:  The aim of this systematic review was to critically evaluate the evidence regarding the adverse effects (AEs) of homeopathy. Method:  Five electronic databases were searched to identify all relevant case reports and case series. Results:  In total, 38 primary reports met our inclusion criteria. Of those, 30 pertained to direct AEs of homeopathic remedies; and eight were related to AEs caused by the substitution of conventional medicine with homeopathy. The total number of patients who experienced AEs of homeopathy amounted to 1159. Overall, AEs ranged from mild-to-severe and included four fatalities. The most common AEs were allergic reactions and intoxications. Rhus toxidendron was the most frequently implicated homeopathic remedy. Conclusion:  Homeopathy has the potential to harm patients and consumers in both direct and indirect ways. Clinicians should be aware of its risks and advise their patients accordingly.

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    ABSTRACT: Background Homeopathy system of medicine is traditionally considered to be one of the safest system of medicine, as the drugs are made from the dilution of the active ingredients [1]. But there are certain evidences available which support the fact that homeopathic medicines can cause severe adverse drug reaction (ADRs) in children [2,3]. It is very important to know the patient medication history to find out the presence of such incidences. The present case of a 5 year old child shows the presence of fever, loose motion and weight loss due to consumption of homeopathy medicine. It is very important to report such cases so that the physicians can be made aware regarding the ADRs pertaining to the use of alternative system of medicine. Case presentation A 5 year old girl presented at our outpatient clinic for fever, loose motion and weight loss. The initial workup was negative for common causes and she had received multiple antibiotics without any specific diagnosis. However none of the treatments were effective. A continuous measurement of the weight and fever were carried out. It was found that her body weight declined from 18 kg to 12 kg (30 % of total weight) with persistent fever of up to 102 F during the observation period of approximately 1 month. She was admitted and various diagnostic tests and cultures were performed to rule out the possibilities of HIV, typhoid, TB and other infectious & non infectious causes. All the tests performed were found negative. From the patient medication history it was found, that apart from the allopathic medicines, the patient was receiving homeopathic medicines for small hypopigmented patches on her right eyelid. On retrospective review, the mother clearly appreciated that the symptoms of fever, loose motion and weight loss started soon after the start of homeopathic treatment. All the medicines were stopped & symptoms resolved soon after withdrawn of homeopathic medicine. Over the next 3 months the child gained all the lost weight and resumed normal activity. We conclude that the most reasonable explanation for the symptoms appears to be homeopathic medicines in this case, since the symptoms are very closely temporally associated with their use. Unfortunately, we were unable to find the name of the exact homeopathic medication used or its potency. No specific treatment is given. Antibiotic therapy and homeopathic treatment were stopped. The child was followed up for a period of one month on weekly basis, before admission, and later monthly for the next 6 months after discharge. Discussion Homeopathic medicine was found to be most likely causative agent for the present symptoms, because the symptoms were start observing soon afterwards the start of the homeopathic treatment. The possibility of all other known reasons for the symptoms was ruled out by the help of various examinations performed in the patients. The findings were further supported by the fact the patient start gaining weight as soon as these homeopathic medicines were withdrawn. Like all other medicines, homeopathic medicines may also produce Rajiv Ahlawat et al. / International Journal of Pharma Sciences and Research (IJPSR) ISSN : 0975-9492 Vol 5 No 08 Aug 2014 478
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    ABSTRACT: For citation purposes: Lenger K, Lang G. Photons detected by magnetic resonance are efficious in homeopathy: a criti-cal review. OA Alternative Medicine 2014 Feb 22;2(1):4. Abstract Introduction Homeopathy, a complementary healing method to cure body and mind, was founded by Samuel Hahnemann (1755–1843). He produced highly potentised reme-dies from minerals, plants, venoms or animals, and succussed them 10 times after every dilution step. From the exceeded Avogadro constant, it had been clarified that there were no molecules left in the highly diluted solutions. According to Hahnemann's Law of Similars (similia similibus curentur), patients had been cured administering minute doses of a remedy. According to this principle, the symptoms produced by any substance on a group of healthy individuals are similar to those in a sick person by application of the same substance, which is then used in high dilution. The actual reason of healing in the patients could not be found: whether it is patient's belief or an energy. Many trials had been carried out, although no one knows the conditions to start an experiment that was reproducible. After the detection of photons in homeopathic remedies by Lenger, a new thinking of homeopathic fundamental laws and research experiments is dis-cussed in this critical review. Finally, a biochemical and biophysical model of homeopathic function is discussed. Conclusion The credibility of homeopathy including the production of homeo-pathic remedies, the reproducibility of provings, clinical trials and research experiments will give it a chance to obtain a scientific base and appreciation in natural sciences. This is a propensity for ill people being cured without any side effects and esoteric ideas.
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    ABSTRACT: According to a contemporary model of homeopathic function, photons detected from remedies with an associated magnetic vector potential and demonstrable frequencies in the MHz-region probably excite substrate-enzyme-complexes along pathological pathways in patients. Substrates in high potencies regulate these pathways as well as their reversible and irreversible inhibitors in XMK or LMK potencies, in chronic diseases. Hashimoto disease could be cured by using the highly-potentized inhibitors of calcium metabo-lism such as Platinum metallicum, Silicea and Alumina by affecting a reaction chain involved in regulating the immune system. Furthermore, when the substrates of the thyroid enzyme metabolism are given in high potencies, such as Kalium iodatum, Iodium, TSH, Thyroxine, Triiodo-thyroninum in XMK potency administered twice a week, thyroid antibodies vanished after three to four months. When the symptom of a dry cough is present, it indicates two different biochemical pathways: firstly, the respiration chain enzymes, and secondly, the nerve-muscle-system leading to paralysis may be involved. A case of cough associated with a lack of iron in the respiratory chain was initially healed by the inhibitors Kalium cyanicum LMK and Hydrocyanicum acidum LMK, followed by the substrates of the respiratory chain: Ferrum metallicum LMK, Cuprum metallicum LMK and Coenzyme Q LMK. A case of paralysis of the chest muscles in asthmatic cough was cured by the irreversible inhibitor of acetylcholine receptor Naja tripudians LMK, the reversible inhibitors Belladonna LMK or Atropinum XMK and by the substrate Acetylcholine XMK. Paralyses concerning the destruction of the membranes were healed by Tetanotoxinum LMK as an irreversible inhibitor, Lecithinum LMK as an associated substrate as well as other unsaturated fatty acids such as EPA LMK. Potent remedies of the enzyme acetylcholinesterase were Dendroaspis LMK as an irreversible inhibitor, Alumina LMK as a reversible inhibitor and Acetylcholin XMK as a substrate. These results lead to the conclusion that remedies associated with irreversible inhibitors act to counteract the syphilitic miasm, reversible inhibitors the sycotic miasm, and substrates the psora miasm. This explains the symptom pictures of Psora, Sycosis and Syphilis in biochemical terms. If the pathological pathways are known, the most appropriate remedies might be found to act as substrates, reversible and irreversible inhibitors of the known biochemical pathways.

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