Low Bone Mineral Density, Regardless of HIV Status, in Men Who Have Sex With Men

Department of Internal Medicine, Division of Infectious Diseases, Center for Infection and Immunity Amsterdam.
The Journal of Infectious Diseases (Impact Factor: 5.85). 11/2012; 207(3). DOI: 10.1093/infdis/jis687
Source: PubMed

ABSTRACT A high prevalence of low bone mineral density (BMD) has been reported in primary and chronic HIV-infected men. To gain further insight into the contribution of HIV-infection, we compared the BMD of 41 primary and 106 chronic HIV-infected men who have sex with men (MSM) with the BMD of a control group of 30 HIV-negative MSM. Low BMD, defined as a Z-score ≤ -2.0 SD at the lumbar spine or hip, was highly prevalent in all three groups. In the multivariate analyses, HIV-infection was not associated with BMD, suggesting that low BMD previously reported in HIV-infected MSM may pre-date HIV-acquisition.

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