Infected lingual osseous choristoma. Report of a case and review of literature

Department of Head and Neck/Maxillofacial Surgery, Greek Anticancer Institute, St. Savvas Hospital, 171 Alexandras Avenue, Athens, 115 22, Greece.
Medicina oral, patologia oral y cirugia bucal (Impact Factor: 1.17). 11/2008; 13(10):E627-32.
Source: PubMed

ABSTRACT Osseous choristoma is a rare, benign lesion of the oral cavity occurring usually in the tongue. It appears as a tumorous mass of normal bony structure with mature cells in an ectopic position. The case of a 72 years Caucasian male is presented and analyzed along with 52 similar cases reported in the English literature between 1967 and 2007. Lingual choristoma shows a female predilection, whereas the commonest anatomic location is the posterior third of the tongue, occurring at or close to the foramen caecum and the circumvallate papillae. Histologically the lesions show signs of a well-circumscribed mass of vital bone located under the surface oral epithelium. Some lesions represent developmental malformations, whereas others may be reactive lesions after trauma or chronic irritation. Treatment of lingual osseous choristoma consists of simple excision.

Download full-text


Available from: Evanthia Chrysomali, Sep 29, 2015
28 Reads
  • [Show abstract] [Hide abstract]
    ABSTRACT: The range of pathology seen in the head and neck region is truly amazing and to a large extent probably mirrors the complex signaling pathways and careful orchestration of events that occurs between the primordial germ layers during the development of this region. As is true in general for the entire discipline of pediatric pathology, the head and neck pathology within this age group is as diverse and different as its adult counterpart. Cases that come across the pediatric head and neck surgical pathology bench are more heavily weighted toward developmental and congenital lesions such as branchial cleft anomalies, thyroglossal duct cysts, ectopias, heterotopias, choristomas, and primitive tumors. Many congenital "benign" lesions can cause significant morbidity and even mortality if they compress the airway or other vital structures. Exciting investigations into the molecular embryology of craniofacial development have begun to shed light on the pathogenesis of craniofacial developmental lesions and syndromes. Much more investigation is needed, however, to intertwine aberrations in the molecular ontogeny and development of the head and neck regions to the represented pathology. This review will integrate traditional morphologic embryology with some of the recent advances in the molecular pathways of head and neck development followed by a discussion of a variety of developmental lesions finishing with tumors presumed to be derived from pluripotent/progenitor cells and tumors that show anomalous or aborted development.
    Advances in anatomic pathology 10/2009; 16(5):332-58. DOI:10.1097/PAP.0b013e3181b50571 · 3.23 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Failures in the normal course of embryonic development of the neural tube may give rise to a great variety of defects as the head and neck region develops. Such abnormalities may be manifested in the form of choristomas. The term choristoma applies to a cohesive tumor like mass consisting of normal cells in an abnormal location. Because of their benign tumor like growth and also their developmental pathogenesis, these need to be differentiated from neoplasms. Choristomas should also be distinguished from hamartomas which are tumor like malformations composed of a focal overgrowth of mature normal cells located where they are normally found. Since choristomas may arise from various tissues, mimicking various neoplasms, this review highlights the pathogenesis of different types of choristomas in the oral cavity.
    05/2012; 24(2):110–114. DOI:10.1016/j.ajoms.2011.11.005
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: An 11-year-old male Belgian shepherd dog was evaluated for a one-week history of progressive lethargy, decreased appetite and excessive panting. On physical examination, a pedunculated mass protruding from the right side of the tongue base was observed. The mass was solid, irregular and multi-lobulated, and it measured approximately 4 × 2 cm. The mass was surgically excised. The histological examination was consistent with a lingual osteoma and the margins were free of neoplastic cells. The dog was euthanased eight months after the diagnosis because of an unrelated problem and no evidence of recurrence at the surgical site was appreciated at that time. To the author's knowledge, this is the first report of a lingual osteoma in a dog, and, therefore, it should be included in the differential diagnosis of masses on the tongue, especially pedunculated masses located at the base of the tongue.
    Journal of Small Animal Practice 08/2012; 53(8):480-2. DOI:10.1111/j.1748-5827.2012.01241.x · 1.09 Impact Factor
Show more