Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute of Medical Research, University of Cambridge, CB2 0XY, UK.
Nature (Impact Factor: 42.35). 11/2007; 450(7171):887-892. DOI: 10.1038/nature06406

ABSTRACT The major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility to more common diseases than any other region of the human genome, including almost all disorders classified as autoimmune. In type 1 diabetes the major genetic susceptibility determinants have been mapped to the MHC class II genes


Available from: Alexandra S Whale, Dec 12, 2014
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