Article

Nipple-sparing mastectomy--initial experience at a tertiary center.

Department of Surgery, Mayo Clinic, Rochester, MN, USA.
American journal of surgery (impact factor: 2.36). 11/2008; 196(4):575-7. DOI:10.1016/j.amjsurg.2008.06.022 pp.575-7
Source: PubMed

ABSTRACT Nipple-sparing mastectomy (NSM) combines skin-sparing mastectomy with preservation of the nipple-areolar dermis and intraoperative pathologic assessment of the nipple core. We evaluated our initial experience with NSM in terms of clinical outcomes.
An Institutional Review Board-approved retrospective review of patients undergoing NSM between November 2005 and June 2007 was performed.
Eighteen NSM and two areola-sparing mastectomies were performed. Indications for surgery were invasive cancer (n = 4), ductal carcinoma in situ (DCIS) (n = 5), pseudoangiomatous stromal hyperplasia (n = 3), and risk reduction (n = 8). The average distance of tumor from the nipple on imaging was 4.8 cm (range 4 to 5.7). Nipple cores were all benign, and 2 patients developed self-limited superficial desquamation of the nipple. At a mean follow up of 10.8 months, all nipple-areolar complexes were intact, and there were no local or systemic recurrences.
NSM can be successfully achieved with low morbidity in appropriately selected patients.

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Keywords

2 patients
 
appropriately
 
clinical outcomes
 
ductal carcinoma
 
Indications
 
initial experience
 
Institutional Review Board-approved retrospective review
 
intraoperative pathologic assessment
 
low morbidity
 
Nipple-sparing mastectomy
 
pseudoangiomatous stromal hyperplasia
 
range 4
 
risk reduction
 
self-limited superficial desquamation
 
skin-sparing mastectomy
 
systemic recurrences
 
tumor