Treating Cancer-Related Fatigue: The Search for Interventions That Target Those Most in Need

Jonsson Comprehensive Cancer Center at University of California, Los Angeles, Los Angeles, CA.
Journal of Clinical Oncology (Impact Factor: 17.88). 10/2012; 30(36). DOI: 10.1200/JCO.2012.46.0436
Source: PubMed
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    ABSTRACT: Background and Objective:The Fatigue related to cancer is one of the common problems of both patients and care-givers. Nowadays, acupressure as a complementary medicine has become more common in patients with cancer for balancing and improving body energy. This study aimed to assess the effect of acupressure on the fatigue of patients with cancer. Material and Methods:This blinded- randomized clinical trial was conducted on 85 patients with cancer in hematology ward of Beheshti hospital of Hamadan. The subjects were located in three groups of intervention, sham and control. First, the fatigue level was measured by Brief Fatigue Inventory (BFI) as a baseline. Then, real acupressure in intervention group and unreal acupressure in sham group was performed for 10 days and only routine cares were given in control group. The fatigue amount was measured on the fifth and tenth days. The Data was analyzed by SPSS software version 16, using paired T- test and repeated measurements. Results:Acupressure was effective on the fatigue of patients with cancer (p<0.001). However, conducting unreal acupressure in sham group was effective as well (p<0.01), but the routine cares in control group was not effective and even in some cases led to increased fatigue. Conclusion:Acupressure can be used as a complementary therapy to decrease the fatigue in the patients with cancer considering its low cost, safety and simplicity.
  • Focus on Alternative and Complementary Therapies 03/2014; 19(1). DOI:10.1111/fct.12082
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    ABSTRACT: Malignant tumors and their various treatments such as chemotherapy, radiotherapy and hormonal therapy can deleteriously affect a large number of cancer patients and survivors on multiple dimensions of psychosocial and neurocognitive functioning. Oncology researchers and clinicians are increasingly cognizant of the negative effects of cancer and its treatments on the brain and its mental processes and cognitive outcomes. Nevertheless, effective interventions to treat cancer and treatment-related neurocognitive dysfunction (CRND), also known as chemobrain, are still lacking. The paucity of data on effective treatments for CRND is due, at least partly, to difficulties understanding its etiology, and a lack of reliable methods for assessing its presence and severity. This paper provides an overview of the incidence, etiology, and magnitude of CRND, and discusses the plausible contributions of psychological, motor function, and linguistic and behavioral complications to CRND. Strategies for reliable neuropsychological screening and assessment, and development and testing of effective ways to mitigate CRND are also discussed.
    Supportive Care in Cancer 03/2014; DOI:10.1007/s00520-014-2162-y · 2.50 Impact Factor