Zoster sine herpete with thoracic motor paralysis temporally associated with thoracic epidural steroid injection
Reactivation of latent varicella-zoster virus can occur when the immune system is weakened leading to the typical presentation seen with herpes zoster or shingles. In a small percentage of these patients, motor paralysis can be seen in the affected myotomal distribution. Zoster sine herpete, or shingles without the typical vesicular rash, is an uncommon variant of zoster. Systemic steroids are known to weaken the immune response. Two previous case reports have implicated epidural steroid injections as a precipitating cause of zoster. We present a case of serologically verified zoster sine herpete producing an abdominal wall bulge, which occurred 1 wk after thoracic epidural steroid injection. Electromyography documented the presence of abdominal wall denervation. Given the low incidence of serologically proven zoster sine herpete--especially with thoracic motor paralysis--and the equally rarely documented incidence of zoster related to epidural steroids, we present what we believe to be the first reported case of zoster sine herpete with a neuropathic abdominal wall bulge occurring in close temporal association to receiving epidural steroids.
Available from: Michael John Yelland
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ABSTRACT: There are several skin and breast lesions that can cause pain or tenderness. In most cases the presence of a skin lesion, if not its definitive diagnosis, will be clinically evident. In most instances treatment of these painful skin lesions is by simple excision, which will also provide histologic confirmation of the diagnosis. It would be rare for a cutaneous cause of skin pain to be mistaken for another cause. The prodromal pain of herpes zoster is most likely to cause diagnostic confusion. The painful skin lesions are usually identified by the patient as being the source of their discomfort. The specific diagnosis may not be apparent without submission of lesional tissue for histology. Chest pain is an uncommon presenting symptom of benign and malignant breast lesions. Breast examination and investigation may be appropriate when other causes of chest pain are not evident.
The Medical clinics of North America 03/2010; 94(2):319-25. DOI:10.1016/j.mcna.2010.01.006 · 2.61 Impact Factor
Clinical neurology and neurosurgery 12/2010; 112(10):933. DOI:10.1016/j.clineuro.2010.06.013 · 1.13 Impact Factor
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ABSTRACT: Herpes zoster is a distinct clinical syndrome that may present with a segmental zoster paresis. Although thoracic dermatomes are the most commonly affected, paresis of the abdominal muscles has been less frequently reported. To review the existing published evidence regarding this unusual clinical entity, a literature search of PubMed and Google was performed. In total, 35 articles that described 36 individual cases were identified. The information from all the cases was tabulated for the analysis. The mean age was 67.5 years. The ratio of men to women was approximately 4:1. The left and right side were approximately equally affected. The most affected associated dermatome was T11. In 88.9% of the patients, the typical herpetic rash preceded the abdominal weakness. The mean latent period from rash to onset of abdominal muscle weakness was 3.5 weeks. Electrodiagnostic studies confirmed the diagnosis in 95% of the tested patients. Complete recovery with conservative measures occurred in 79.3% of the patients who were followed-up for recovery, with a mean time for recovery of 4.9 months. Visceral neuropathy co-occurred in 19.4% of the patients. Because of its self-limited nature and good prognosis, recognition of this complication is important to prevent unnecessary diagnostic studies and procedures. Electrodiagnostic studies can be effectively used to confirm the diagnosis. Because visceral neuropathy commonly co-occurs with segmental zoster abdominal paresis, it should be actively investigated and treated.
PM&R 09/2013; 5(9):786-90. DOI:10.1016/j.pmrj.2013.05.013 · 1.53 Impact Factor
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