Liver metastasis in a case of adenoid cystic carcinoma of the Bartholin's gland: A rare presentation

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY 10461, USA.
Archives of Gynecology (Impact Factor: 1.36). 10/2008; 279(5):747-50. DOI: 10.1007/s00404-008-0771-8
Source: PubMed


Adenoid cystic carcinoma of the Bartholin's gland accounts for a minority of all Bartholin's gland malignancies. Although local recurrences commonly occur distant metastasis is rare.
We present the first reported case of Adenoid cystic carcinoma of the Bartholin's gland with metastasis to the liver.
There is no consensus on the treatment of adenoid cystic carcinoma of the Bartholin's gland. Wide local excision and/or vulvectomy and radiotherapy are advocated for treatment of this cancer. There is not much data on treatment of metastasis and it varies according to site.

1 Read
  • [Show abstract] [Hide abstract]
    ABSTRACT: Adenoid cystic carcinoma is the most frequent pathology occurring in the minor salivary glands .It is usually slow growing; however, it can spread via perineural invasion, haematogenous and lymphatogenous metastasis. Most common sites of metastasis are lung and bone. Involvement of the other sites is not common. In this article, we present a woman with coincident lung and liver metastases.
    Case Reports 02/2013; 2013(feb27 1). DOI:10.1136/bcr-01-2012-5658
  • [Show abstract] [Hide abstract]
    ABSTRACT: Most lesions of the Bartholin gland are cysts or abscesses. Clinicians are taught that lesions of the Bartholin gland occurring in older women should raise the differential diagnosis of malignancy, although these are uncommon. Avariety of more unusual and rare lesions of the Bartholin gland have been reported. This review focuses on these less common entities, which must be considered as well when encountering pathology of the Bartholin gland. © 2014, American Society for Colposcopy and Cervical Pathology.
    Journal of Lower Genital Tract Disease 06/2014; 18(4). DOI:10.1097/LGT.0000000000000016 · 1.99 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Adenoid cystic carcinoma of Bartholin's gland is a rare malignant tumor of female genital tract. We report a case of a 42-year-old woman, presenting a palpable painful mass and burning sensation on the left side of vulva during the preceding two months. Based on examination, a solid fixed painful nodule with intact mucosa was palpated on the left side of the vagina. Histological features were compatible with adenoid cystic carcinoma. Often, such lesion is clinically misdiagnosed as a cyst or inflammation. The present case was carried out with an impression of endometriosis. The possibility of cancer should be considered in any female older than 40 years of age with a lesion near the Bartholin's glands.
    Iranian Journal of Medical Sciences 11/2014; 39(6):580-583.