Distribution of Different Species of the Bacteroides fragilis Group in Individuals with Japanese Cedar Pollinosis

Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa 228-8583, Japan.
Applied and Environmental Microbiology (Impact Factor: 3.67). 10/2008; 74(21):6814-7. DOI: 10.1128/AEM.01106-08
Source: PubMed


We investigated associations of species of the Bacteroides fragilis group with Japanese cedar pollinosis (JCPsis). Cell numbers of Bacteroides fragilis and Bacteroides intestinalis were significantly higher in JCPsis subjects than in non-JCPsis subjects before the pollen season. They correlated positively
with both symptom scores and JCPsis-specific immunoglobulin E levels.

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    • "These results were attributed to immunomodulation of a T-helper 2 (Th2)-mediated immune response [102] and to a "stabilization" of fluctuations in the composition of the patients' fecal microbiota [107,108]. In contrast, in this same group, numbers of Bacteroides fragilis and Bacteroides intestinalis were significantly higher among JCP-allergic patients and correlated positively with symptom scores and JCP-specific IgE levels [109]. "
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    • "lture period , showed 99 . 9% 16S rRNA gene sequence identity to that of the type strain of B . intestinalis JCM13265 T . Bacteroides intestinalis was recently identified as a human intestinal bacterium ( Bakir et al . , 2006 ) . Recent investigation revealed the population of B . intestinalis to be about 10 8 . 5 g – 1 of the human fecal sample ( Odamaki et al . , 2008"
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