Surgical case of giant malignant mesenchymoma in the posterior mediastinum that recurred in the bilateral mediastinum.

Department of Biological Regulation and Regenerative Surgery, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
Journal of Nippon Medical School (Impact Factor: 0.59). 09/2008; 75(4):212-5. DOI: 10.1272/jnms.75.212
Source: PubMed

ABSTRACT Malignant mesenchymoma is a soft-tissue tumor arising preferentially in the extremities and the retroperitoneum. We report a case of primary malignant mesenchymoma of the left side of the posterior mediastinum with local recurrence on both sides of the mediastinum. A 24-year-old woman was admitted to our hospital complaining of cough. Chest X-ray showed a giant mass in two-thirds of the left lung field, and computed tomography of the chest revealed a lobulated large mass with a fat-density area and a calcified spot in the mediastinum and left pleural space. Magnetic resonance of the chest demonstrated a large, solid mass consisting mainly of areas with the same intensity as fatty tissue and partly of areas of heterogeneous moderate intensity. The tumor was resected completely through a left posterolateral thoracotomy. The pathologic diagnosis was malignant mesenchymoma: well-differentiated liposarcoma with osteocartilagenous differentiation. The patient had local recurrence in both sides of the mediastinum 3 years and 6 months after surgery, and the recurrent tumors were completely resected again.