To determine whether women will experience permanent amenorrhea following uterine artery embolization for fibroids, and whether rates of onset differ in the long term according to age at the time of the procedure.
Over 77 months, 211 consecutive eligible women were grouped by age (group A, <40 years [n=39]; group B, 40-44 years [n=98]; and group C, > or =45 years [n=74]) and the cumulative rates of onset of permanent amenorrhea were compared between the groups.
The likelihood of incurring permanent amenorrhea was significantly higher in group C. The cumulative rates in groups A, B, and C were 0%, 1.4%, and 19.7% at 3 years and 0%, 11.2%, and 40.4% at 6 years.
The rates of onset of permanent amenorrhea changed over time and differed according to age at the time of the procedure, with little likelihood of permanent amenorrhea at 6 years for women younger than 40 years at the time of the procedure.
[Show abstract][Hide abstract] ABSTRACT: This was a single-site cohort study to evaluate the safety of a new transcervical device (VizAblate™) combining real-time
intrauterine sonography with radiofrequency (RF) ablation for the treatment of fibroids. Nineteen women with uterine fibroids
received treatment with the VizAblate System in a closed abdomen setting prior to hysterectomy. Twelve of these subjects underwent
an immediate abdominal hysterectomy after radiofrequency ablation (acute group), while the remaining seven underwent hysterectomy
on post-ablation days16 and 17 (subacute group). Uteri were sectioned and stained with the viability stain triphenyltetrazolium
chloride (TTC) to quantify fibroid ablation dimensions and assess the serosa for thermal injury. Subjects in the subacute
group were treated with the VizAblate System under conscious sedation; they provided pain and tolerability data for the interval
from ablation through hysterectomy, and indicated overall procedural satisfaction. Twenty-two ablations ranging from 1.8 to
36.2cm3 were created among 19 subjects within 20 fibroids and one region of adenomyosis. There were no complications or thermal serosal
injury. For subjects in the subacute group receiving one ablation, the mean total procedure time was 25.8 ± 6.0min (range
18–32min). All subjects in the subacute group were discharged within 2h of the VizAblate procedure. For fibroids ≤ 5cm,
67.2% ± 27.0% of the fibroid volume was ablated (range 15–100%; median 75%). Transcervical RF ablation of fibroids under intrauterine
sonographic guidance with the VizAblate system can be accomplished with a high degree of reliability and without adverse events.
KeywordsRadiofrequency ablation–Fibroids–Intrauterine sonography–Myomata
Gynecological Surgery 09/2011; 8(3):327-334. DOI:10.1007/s10397-010-0655-3
[Show abstract][Hide abstract] ABSTRACT: As the voltage and current waveforms are deformed due to transient during faults, their pattern changes according to the type of fault. The artificial neural network (ANN) can then be used for fault detection due to its distinguished behavior in pattern recognition. In order to minimize the structure and timing of the ANN, preprocessing of the voltage and current waveforms was done. The data delivered from a simulated power system using PSCAD (EMTP with cad system) was used for training and testing the ANN. An experimental setup, consists of a 3 phase power supply module and transmission line module, is utilized. A set of signal conditioning circuits is designed and implemented in order to transfer data to a PC which is used as an online relay for fault detection. This is done via a data acquisition card (CIO-DAS1602/12). The Matlab program captures and processes real data for training the ANN. Applying different types of faults for testing the system, right tripping action was taken and the type of fault was correctly identified. The suggested artificial neural network algorithm has been found simple and effective hence could be implemented in practical application.
Power System Technology, 2004. PowerCon 2004. 2004 International Conference on; 12/2004
[Show abstract][Hide abstract] ABSTRACT: Uterine artery embolization (UAE) is assuming an important role in the treatment of women with symptomatic uterine leiomyomata worldwide. The following guidelines, which have been jointly published with the Society of Interventional Radiology in the Journal of Vascular and Interventional Radiology, are intended to ensure the safe practice of UAE by identifying the elements of appropriate patient selection, anticipated outcomes, and recognition of possible complications and their timely address.
Journal of vascular and interventional radiology: JVIR 07/2009; 20(7 Suppl):S193-9. DOI:10.1016/j.jvir.2009.04.006 · 2.41 Impact Factor
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