Maternal, prenatal and perinatal characteristics and first trimester maternal serum hormone concentrations

Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, 6120 Executive Boulevard, Rockville, MD 20892-7246, USA.
British Journal of Cancer (Impact Factor: 4.84). 10/2008; 99(7):1161-4. DOI: 10.1038/sj.bjc.6604639
Source: PubMed


In uncomplicated pregnancies, first trimester androgen, oestrogen and prolactin concentrations were higher in nulliparous (n=160) than parous (n=260) mothers. Androgens and estrogens were higher in younger than older mothers. These data are consistent with elevated hormone concentrations mediating the breast cancer protection from a first pregnancy and pregnancies occurring at younger ages.

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