Article

Axial Elongation following Cataract Surgery during the First Year of Life in the Infant Aphakia Treatment Study

Department of Ophthalmology, Emory University, Emory Eye Center, 1365-B Clifton Rd, Atlanta, GA, 30322, United States.
Investigative ophthalmology & visual science (Impact Factor: 3.66). 10/2012; 53(12). DOI: 10.1167/iovs.12-10285
Source: PubMed

ABSTRACT PURPOSE: To compare ocular axial elongation in infants after unilateral cataract surgery corrected with a contact lens (CL) or primary intraocular lens (IOL) implantation. Methods: Baseline axial length (AL) was measured at the time of cataract surgery (1-6 months) and at age 1 year. AL at baseline and age 1 year of age and the change in length/month were analyzed in relation to treatment modality, cataractous vs. fellow eye and age at surgery using linear mixed models. RESULTS: Mean baseline AL did not differ between the CL and IOL groups for either cataractous or fellow eyes. Eyes with cataracts were shorter than fellow eyes by an average of 0.6 mm (95% CI, 0.4 - 0.8 mm; p < 0.0001). For the operated eyes the mean change in AL/month was smaller in the CL group (0.17 mm/mo) than in the IOL group (0.24 mm/mo) (p = 0.0006) and was independent of age at surgery (p = 0.19). In contrast, the change in AL/month for fellow eyes decreased with older age at surgery (p < 0.0001). At age 1 year, operated eyes treated with a CL were 0.6 mm shorter on average than operated eyes treated with an IOL (p = 0.009). CONCLUSIONS: At baseline, eyes with cataracts were shorter than fellow eyes. The change in AL/month was smaller in operated eyes treated with a CL than in operated eyes treated with an IOL, but was not significantly related to age at surgery.

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