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Using the Autism Diagnostic Interview-Revised and the Autism Diagnostic Observation Schedule-Generic for the Diagnosis of Autism Spectrum Disorders in a Greek Sample with a Wide Range of Intellectual Abilities

Department of Child Psychiatry Agia Sofia Children's Hospital, University of Athens, Goudi, 11527, Athens, Greece.
Journal of Autism and Developmental Disorders (Impact Factor: 3.06). 09/2008; 39(3):414-20. DOI: 10.1007/s10803-008-0639-6
Source: PubMed

ABSTRACT We studied the interrelationship between the Autism Diagnostic Observation Schedule-Generic (ADOS-G), the Autism Diagnostic Interview-Revised (ADI-R) and DSM-IV clinical diagnosis, in a Greek sample of 77 children and adolescents, referred for the assessment of a possible pervasive developmental disorder (PDD) and presenting a wide range of cognitive abilities. The agreement of the ADOS-G and the ADI-R with the clinical diagnosis was estimated as satisfactory and moderate, respectively, while both instruments presented with excellent sensitivity for the diagnosis of autistic disorder along with satisfactory specificity. ADOS-G/ADI-R agreement was estimated as fair. Our results confirm the discriminant validity of ADI-R and ADOS-G in diagnosing pervasive developmental disorders in children and adolescents with a wide range of intellectual abilities.

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    • "Diagnostic assessments have been conducted using standardised instruments: ADOS (Li, Zhong, Cai, Chen, & Zhou, 2005) and the ADI-R (Le-Couteur et al., 1989; Lord, Rutter, & Le Couteur, 1994; Rutter et al., 2003). The combined use of the ADOS and the ADI-R has been widely adopted in both research and clinical settings (Papanikolaou et al., 2009), although its limitations are acknowledged (e.g., it is better at detecting classic autism than Asperger Syndrome, especially in adulthood). The Chinese versions of both instruments were provided by the publisher (World Psychological Service, WPS). "
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    • "It consists of four modules, all of which have shown good reliability, sensitivity and specificity for both autism and ASD, both in its English and Spanish forms (Lord, Rutter, DiLavore, & Risi, 2006). The ADOS has also been used in other countries such as Greece (Papanikolaou et al., 2009) and Germany (Bölte & Poustka, 2004), and its psychometric properties were confirmed in these versions. "
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