Pharmacological Treatment of Kleptomania and Bulimia Nervosa

Biological Psychiatry Laboratory, McLean Hospital, Belmont, Massachusetts 02178.
Journal of Clinical Psychopharmacology (Impact Factor: 3.24). 09/1989; 9(5). DOI: 10.1097/00004714-198910000-00008


We describe three patients with concurrent DSM-III-R kleptomania and bulimia nervosa who all demonstrated a partial or complete response of both bulimic and kleptomanic symptoms to fluoxetine, trazodone, or tranylcypromine. These observations raise the possibility that pharmacological treatment may benefit kleptomania, and call for further study of the relationship between kleptomania, bulimia nervosa, and major depression.
(C) Williams & Wilkins 1989. All Rights Reserved.

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    • "According to O'Guinn and Faber (1989), compulsive consumption behaviours may include compulsive buying, pathological gambling , kleptomania, compulsive sexuality and eating disorders (see also Krahn, 1991; McElroy et al., 1995). Compulsive consumption behaviours may also have common causes, similar patterns of development (Hirschman, 1992) and may also be co-morbid (McElroy et al., 1989, 1995; Christenson et al., 1994; Faber et al., 1995; Lee et al., 2000; Mitchell et al., 2002). As several compulsive consumption disorders may interrelate or overlap, it may be highly beneficial to study them as a larger phenomenon (Faber et al., 1995) or to examine whether or not one compulsive behaviour leads to another (Krahn, 1991). "
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    ABSTRACT: Compulsive buying and binge eating are examples of compulsive consumption behaviours, and for individuals with these behavioural tendencies, appearance and appearance-related products seem to be of paramount importance. The purpose of this research was to determine if bulimic behaviours, fashion interest and the importance of being well dressed had a causal relationship with compulsive clothing buying. Subjects completed a compulsive clothing buying scale, the binging/control subscale of the Bulimia Test-Revised and a fashion orientation scale. A path analysis indicated that binging behaviours and fashion interest significantly predicted compulsive clothing buying, while binging behaviours were not significantly related to fashion interest or the importance of being well dressed. Such findings may suggest that female consumers compulsively buy clothing for different reasons and/or motivations.
    International IJC 04/2009; 33(3):267 - 273. DOI:10.1111/j.1470-6431.2009.00741.x · 0.66 Impact Factor
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    • "Serotonin reuptake inhibitors, considered first-line treatment for OCD [34], have been shown to be effective in treating impulsivity in other ICDs and OC spectrum disorders [35-39]. Furthermore, neurobiological data indicating serotonergic dysfunction in PG [40-42], a phenomenological link to compulsivity [8], and a possible response in PG to the SRI clomipramine [43], have given further support for the use of the SRIs in this disorder. "
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    ABSTRACT: Pathological Gambling (PG) is an impulse control disorder often comorbid with other psychopathology, particularly bipolar spectrum disorders, attention deficit/hyperactivity disorder, obsessive-compulsive disorder (OCD) and substance abuse. This paper reviews the published literature on the pharmacological management of PG, highlighting how clinical and subclinical comorbid psychopathology influences the choice of pharmacological treatment. Using Medline, the authors reviewed relevant articles published on this topic from 1995 to 2005, focusing on the best-designed studies for inclusion. Much of the literature on PG-treatment presupposes different theories regarding this disorder. Data suggest the utility of differentiating the pharmacotherapy of pathological gamblers in light of their comorbid profile, specifically assessing for comorbid bipolar, ADHD, OCD, and substance abuse disorders. Decisions about pharmacological treatment of PG should take into account current and previous comorbid disorders which influence treatment selection.
    Clinical Practice and Epidemiology in Mental Health 11/2005; 1(1):21. DOI:10.1186/1745-0179-1-21
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