Article

Acute generalized exanthematous pustulosis due to clindamycin.

Resurrection Hospital, Chicago, IL, USA.
Dermatology online journal 02/2008; 14(7):14. pp.14
Source: PubMed

ABSTRACT Acute generalized exanthematous pustulosis (AGEP) is a rare skin eruption most commonly caused by medications. It is characterized by fever and the acute eruption of non-follicular pustules overlying erythrodermic skin. Histopathology shows subcorneal pustules with a background of dermal edema and spongiosis, leukocytoclastic vasculitis, perivascular eosinophils, and focal necrosis of keratinocytes. Three cases of clindamycin induced AGEP have been reported in the literature. A case of AGEP due to clindamycin is reported in a patient with numerous other drug allergies and without history of psoriasis. Presentation and treatment of AGEP are reviewed.

0 0
 · 
0 Bookmarks
 · 
23 Views
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

acute eruption
 
Acute generalized exanthematous pustulosis
 
cases
 
clindamycin
 
clindamycin induced AGEP
 
dermal edema
 
drug allergies
 
focal necrosis
 
Histopathology
 
leukocytoclastic vasculitis
 
medications
 
non-follicular pustules overlying erythrodermic skin
 
perivascular eosinophils
 
subcorneal pustules