Comorbidities of Bladder pain syndrome/interstitial cystitis: A population-based study

School of Public Health, Taipei Medical University Department of Urology, Taipei County Hospital School of Health Care Administration, Taipei Medical University, Taipei, Taiwan.
BJU International (Impact Factor: 3.53). 09/2012; 110(11C). DOI: 10.1111/j.1464-410X.2012.11539.x
Source: PubMed


Study Type – System prevalence (cohort)
Level of Evidence 2a
What's known on the subject? and What does the study add?
Compared with the general population, patients with BPS/IC often experience difficulties in performing normal activities owing to physical limitations, decreased energy, greater pain and impaired social functioning
With the exception of metastatic cancer, separate conditional logistic regression analyses in this study suggested that subjects with BPS/IC were consistently more likely than subjects without BPS/IC to have all the medical comorbidities investigated. When compared with subjects without BPS/IC, subjects with BPS/IC had particularly higher odds of comorbid neurological diseases, rheumatological diseases and mental illnesses.

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    ABSTRACT: Bladder pain syndrome is one of the most challenging urological disorders to diagnose and manage. Symptoms can be highly debilitating for patients. The exact etiology remains unclear although there have been associations with other regional and global functional disorders. The magnitude and duration of symptom response to current therapies can be highly variable amongst patients, and even within an individual patient’s course. A multidisciplinary approach is paramount and optimal therapy may involve multiple simultaneous treatments.
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