A 73-year-old woman with mild shortness of breath and multiple central calcified pulmonary nodules
ABSTRACT The diagnostic workup for multiple calcified pulmonary nodules can be a challenge for clinicians. The differential diagnosis of multiple calcified pulmonary nodules includes a broad spectrum of etiologies, the most important of which are neoplastic and infectious. A detailed medical history and radiographic description, with particular emphasis on the location and, to a lesser extent, the morphology, number, and size of nodules and other associated radiographic abnormalities usually help to narrow the differential diagnosis. This discussion focuses on the differential diagnosis and the workup of multiple calcified pulmonary nodules.
- Indian Journal of Pathology and Microbiology 01/2012; 55(1):119-20. DOI:10.4103/0377-4929.94882 · 0.64 Impact Factor
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ABSTRACT: A 62-year-old woman was found to have multiple bilateral pulmonary nodules showing different (18)F-fluorodeoxyglucose (FDG) uptakes on positron-emission tomography/computed tomography (PET/CT). Only the largest nodule in the left lower lobe showed an increased (18)F-FDG uptake on PET/CT. Three nodules were surgically resected from different lobes of the left lung. Two lobes were benign and showed amyloid deposition. The largest nodule in the left lower lobe showed adenocarcinoma and a heavy amyloid deposition. Pulmonary amyloidosis should be added to the differential diagnosis for cases with multiple pulmonary nodules that show different (18)F-FDG uptakes on PET/CT. To the best of our knowledge, this is the second reported case of a lung nodule consisting of adenocarcinoma and amyloid deposition.Case Reports in Oncology 09/2014; 7(3):789-98. DOI:10.1159/000369112