Sugar-sweetened beverages and incidence of type 2 diabetes mellitus in African American women

Slone Epidemiology Center, BostonUniversity, Boston, MA 02215, USA.
Archives of internal medicine (Impact Factor: 13.25). 08/2008; 168(14):1487-92. DOI: 10.1001/archinte.168.14.1487
Source: PubMed

ABSTRACT Type 2 diabetes mellitus is an increasingly serious health problem among African American women. Consumption of sugar-sweetened drinks was associated with an increased risk of diabetes in 2 studies but not in a third; however, to our knowledge, no data are available on African Americans regarding this issue. Our objective was to examine the association between consumption of sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes mellitus in African American women.
A prospective follow-up study of 59,000 African American women has been in progress since 1995. Participants reported on food and beverage consumption in 1995 and 2001. Biennial follow-up questionnaires ascertained new diagnoses of type 2 diabetes. The present analyses included 43,960 women who gave complete dietary and weight information and were free from diabetes at baseline. We identified 2713 incident cases of type 2 diabetes mellitus during 338,884 person-years of follow-up. The main outcome measure was the incidence of type 2 diabetes mellitus.
The incidence of type 2 diabetes mellitus was higher with higher intake of both sugar-sweetened soft drinks and fruit drinks. After adjustment for confounding variables including other dietary factors, the incidence rate ratio for 2 or more soft drinks per day was 1.24 (95% confidence interval, 1.06-1.45). For fruit drinks, the comparable incidence rate ratio was 1.31 (95% confidence interval, 1.13-1.52). The association of diabetes with soft drink consumption was almost entirely mediated by body mass index, whereas the association with fruit drink consumption was independent of body mass index.
Regular consumption of sugar-sweetened soft drinks and fruit drinks is associated with an increased risk of type 2 diabetes mellitus in African American women. While there has been increasing public awareness of the adverse health effects of soft drinks, little attention has been given to fruit drinks, which are often marketed as a healthier alternative to soft drinks.

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Available from: Deborah Boggs Bookwalter, Aug 13, 2015
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    • "In 2004, Bray et al. (2004) published a study linking the consumption of high-fructose corn syrup (HFCS)-sweetened beverages to obesity. Since that publication, other epidemiologic studies have shown that chronic consumption of sugar-sweetened beverages are associated with greater rates of obesity, insulin resistance, type 2 diabetes, and heart disease (Bray et al. 2004; Bremer et al. 2010; Fung et al. 2009; Montonen et al. 2007; Palmer et al. 2008; Schulze et al. 2004; Yoshida et al. 2007). Experimental studies have compared the metabolic health effects of different sugar-sweetened beverages O including pure glucose, pure fructose , HFCS, and sucrose O at various doses of sugar intake and consumed for various lengths of time (1 day to 10 weeks) (Aeberli et al. 2011, 2013; Cox et al. 2011, 2012; Le et al. 2006; Stanhope et al. 2008, 2009, 2011a, 2011b; Swarbrick et al. 2008; Teff et al. 2009). "
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    • "During the last decade, there has been an increasing number of published epidemiological and interventional studies on human populations linking the high consumption of sugar-sweetened beverages, enriched in simple sugars such as fructose and glucose, to the high prevalence of chronic metabolic and related cardiovascular diseases [1] [2] [3] [4]. These diseases include dyslipidemia [5] [6], gout [7], hypertension [8] [9], obesity [10] [11], insulin resistance [12] and type 2 diabetes mellitus [10] [13] [14] [15]. High energy intake, lack of adequate energy compensation through a proportional decrease in the amount of energy ingested as solid foods, and the special metabolism of fructose, have been reported to contribute to this possible causal association [2] [3]. "
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