Preliminary Investigation of Antimicrobial Property of Acacia leucophloea Leaves Extract


Leaves of indigenous plant Acacia leucophloea have been successively extracted using different solvents like hexane, methanol and water. Extract was evaluated for its antibacterial activity using two assay method Kirby bauer disc diffusion and tube dilution assay. Results of the given study revealed that the methanolic extract is potential antibacterial agent specifically for E coli & & S aureus.

Download full-text


Available from: Rajeev K Singla, Oct 01, 2015
44 Reads
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Endocarp of C. nucifera L.(Coconut fruit), a universally acceptable waste material is the plant part for our study. Dry distilled extract, RNDS, was prepared using the special procedure adopted by our lab. It was evaluated for its antimicrobial activity using Kirby bauer agar diffusion assay technique. In gram negative- P. aeruginosa & E. coli strains were used and in gram positive – S. aureus & B. subtilis were used, while four fungal strains like A. oryzae, C. albicans, R. oligosporus and A. flavus were part of current study. Results revealed that RNDS is expressing potential growth inhibition of B. subtilis and Aspergillus species. It was inactive against R. oligosporus at all concentrations.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: 1,3-oxazolidin-2-one, an oxygen and nitrogen comprising heterocyclic structure attracts many researchers all over world, evidenced to have unique and potential antibacterial activity. We had designed and synthesized few analogues of 1,3-oxazolidin-2-ones. Their structures were characterized using physical and spectral data. To evaluate their antibacterial potential, Kirby Bauer Agar Diffusion Assay procedure was adopted. Results are very significant and revealed that 1,3-oxazolidin-2-ones have potential antibacterial activity when compared with standard Oxytetracycline. In case of E. coli, unsubstituted parent molecule have better inhibitory effect than the substituted ones while in case of P. vulgaris, substituted analogs have higher effect than the parent one.