Preliminary Comparative Phytochemical Screening of Euphorbia Species
American-Eurasian Journal of Agricultural & Environmental Sciences 09/2012; 11(8).
Phytochemical screening tests were performed first before bulk extractions. Phytochemical screening resulted in the isolation of new and novel compounds proved to be a leading candidate to fight diseases including cancer. Aerial parts of Euphorbia prostrate, Euphorbia milii, Euphorbia hirta and Euphorbia helioscopia were used for phytochemical screening for the presence of different classes of secondary metabolites. The phytochemical screening revealed the presence of terpenoids, flavonides and tennins which are given in table (2-5). The IR spectroscopy of the crude extracts indicated the presence of OH, CH stretching saturated, C=O, C=C, NO2, C-N, Ar-O, C-O- , R-O-, C-Cl Stretching respectively
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ABSTRACT: The crude methanolic extract of aerial parts of Euphorbia milli was tested for its antinociceptive property. The antinociceptive effect was evaluated usin chemical (acetic acid) induced pain paradigm. The acetic acid induced writhing was significantly attenuated by the crude methanolic extract. The mean number of writhing reduction of the crude methanolic extract was 12.34, 32.54 and 71.44 % at the tested doses of 50, 100 and 150 mg/kg respectively. The percent effect of diclofenac sodium was 82.34% was nearest to our tested sample. The crude methanolic extract demonstrated a dose and time dependent effect.