Preliminary Comparative Phytochemical Screening of Euphorbia Species
ABSTRACT Phytochemical screening tests were performed first before bulk extractions. Phytochemical screening resulted in the isolation of new and novel compounds proved to be a leading candidate to fight diseases including cancer. Aerial parts of Euphorbia prostrate, Euphorbia milii, Euphorbia hirta and Euphorbia helioscopia were used for phytochemical screening for the presence of different classes of secondary metabolites. The phytochemical screening revealed the presence of terpenoids, flavonides and tennins which are given in table (2-5). The IR spectroscopy of the crude extracts indicated the presence of OH, CH stretching saturated, C=O, C=C, NO2, C-N, Ar-O, C-O- , R-O-, C-Cl Stretching respectively
SourceAvailable from: Abdur Rauf[Show abstract] [Hide abstract]
ABSTRACT: Desmodium elegans is medicinal plants commonly used for the treatment of jaundice, fever, paralysis, oedema, asthma, cold, constipation, cough, convulsion, cholestylithiasis and urolithiasis. The present investigation intended with various phytochemical screening and biological studies were carried out on the bark of Desmodium elegans. Preliminary phytochemical test of the crude extract and various fractions revealed the presence of, steroids, Saponins, tannins, reducing sugars, cardiac glycosides and caumarines. The antimicrobial activity and Phytotoxicity activities of crude extract and various fractions of D. elegans were investigated. Significance phytotoxic activity was observed at higher concentration. INTRODUCTION healing wounds [3-5]. Previous studies have revealed that
[Show abstract] [Hide abstract]
ABSTRACT: Euphorbia prostrate belongs to family Euphorbiaceae locally known as Doodhi is small annual herb. Current study was conducted to evaluate the gastro protective and antioxidant effectiveness of the aerial parts of E. prostrata in indomethacin induced ulcer in adult male albino rabbits. A total 36 mice were taken and divided into 6 equal groups. At day 0 and 14 of experiment the blood sample was collected from each animal and serum was separated from blood which was used for the determination of Total oxidant status (TOS), Total antioxidant capacity (TAC), catalase (CAT) and Malondialdehyde (MDA). At the end of the experiment, all of the rabbits were slaughtered. The gastric contents were collected to total acid output, gastric pH and gastric volume. To confirm the data results was subjected to one way analysis of variance (ANOVA). Results when compared with the extensive mucosal damage in the indomethacin trated group, gross evaluation revealed a marked protection of the gastric mucosa in the experimental groups, with significantly reduction in gastric pH, gastric volume and acid output. In these groups, CAT and TAC levels were significantly increased (P < 0.05) and while MDA and TOS significantly reduced (P < 0.05) which indicate reduction in gastric damage. In conclusion to these results E. prostrata has potent antioxidant properties at dose rate of 240 mg/kg and it is also very effective for the treatment of gastric ulcer at the same dose.International Research Journal of Pharmacy 11/2014; 2014(511):846-850. DOI:10.7897/2230-8407.0511173
[Show abstract] [Hide abstract]
ABSTRACT: The crude methanolic extract of aerial parts of Euphorbia milli was tested for its antinociceptive property. The antinociceptive effect was evaluated usin chemical (acetic acid) induced pain paradigm. The acetic acid induced writhing was significantly attenuated by the crude methanolic extract. The mean number of writhing reduction of the crude methanolic extract was 12.34, 32.54 and 71.44 % at the tested doses of 50, 100 and 150 mg/kg respectively. The percent effect of diclofenac sodium was 82.34% was nearest to our tested sample. The crude methanolic extract demonstrated a dose and time dependent effect.