Analysis of Obesity-Related Outcomes and Bariatric Failure Rates With the Duodenal Switch vs Gastric Bypass for Morbid Obesity

Archives of surgery (Chicago, Ill.: 1960) (Impact Factor: 4.93). 09/2012; 147(9):847-54. DOI: 10.1001/archsurg.2012.1654
Source: PubMed


OBJECTIVE To compare the outcomes of a large cohort undergoing biliopancreatic diversion/duodenal switch (DS) vs gastric bypass (GB). DESIGN Retrospective review of the Bariatric Outcomes Longitudinal Database from 2007 to 2010. All inpatient and outpatient follow-up data were analyzed. SETTING Multicenter database. PATIENTS Patients undergoing primary DS were compared with a concurrent cohort undergoing GB. MAIN OUTCOME MEASURES The main outcome measures were (1) weight loss; (2) control of comorbidities including diabetes mellitus, hypertension, and sleep apnea; and (3) failure to achieve at least 50% excess body weight loss. RESULTS One thousand five hundred forty-five patients underwent DS and 77 406 underwent GB, with a mean preoperative body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) of 52 and 48, respectively (P < .01). The DS was associated with longer operative times, greater blood loss, and longer lengths of hospital stay (all P < .05). Early reoperation rates were higher in the DS group (3.3% vs 1.5%). Percentage of change in BMI was significantly greater in the DS group at all follow-up intervals (P < .05). Subgroup analysis of the superobese population (BMI >50) revealed significantly greater percentage of excess body weight loss in the DS group at 2 years (79% vs 67%; P < .01). Comorbidity control of diabetes, hypertension, and sleep apnea were all superior with the DS (all P < .05). The risk of weight loss failure was significantly reduced with DS vs GB for all patients, with a greater reduction in the BMI more than 50 subgroup. CONCLUSIONS The DS is a less commonly used bariatric operation, with higher early risks compared with GB. However, the DS achieved better weight and comorbidity control, with even more pronounced benefits among the superobese.

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    • "Morbid obesity is the indication for surgical treatment known as bariatric surgery. There are still discussions concerning which procedure should be performed on a particular patient [1–4]. Although great progress has been achieved in bariatric surgery in recent years, it is still not free of life-threatening complications [5–7]. "
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    Videosurgery and Other Miniinvasive Techniques / Wideochirurgia i Inne Techniki Malo Inwazyjne 06/2014; 9(2):292-6. DOI:10.5114/wiitm.2011.38177 · 1.09 Impact Factor
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    Gastroenterology Research and Practice 10/2013; 2013(8):528450. DOI:10.1155/2013/528450 · 1.75 Impact Factor
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