Repair of a median nerve transection injury using multiple nerve transfers, with long-term functional recovery Case report

Department of Neurological Surgery, and.
Journal of Neurosurgery (Impact Factor: 3.15). 09/2012; 117(5). DOI: 10.3171/2012.8.JNS111356
Source: PubMed

ABSTRACT Complete loss of median nerve motor function is a rare but devastating injury. Loss of median motor hand function and upper-extremity pronation can significantly impact a patient's ability to perform many activities of daily living independently. The authors report the long-term follow-up in a case of median nerve motor fiber transection that occurred during an arthroscopic elbow procedure, which was then treated with multiple nerve transfers. Motor reconstruction used the nerves to the supinator and extensor carpi radialis brevis to transfer to the anterior interosseous nerve and pronator. Sensory sensation was restored using the lateral antebrachial cutaneous (LABC) nerve to transfer to a portion of the sensory component of the median nerve, and a second cable of LABC nerve as a direct median nerve sensory graft. The patient ultimately recovered near normal motor function of the median nerve, but had persistent pain symptoms 4 years postinjury.

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    ABSTRACT: To report our experiences reconstructing thumb and finger flexion in patients with extensive palsy of the upper limb by transferring the radial nerve branch to the extensor carpi radialis brevis (ECRB) to the anterior interosseous nerve (AIN). Within 8 months after injury, 4 patients with either a combined high median/ulnar nerve palsy or C7-T1 brachial plexus root avulsion underwent surgical reconstruction for thumb and finger flexion. As part of the reconstructive procedure, the branch of the radial nerve to the ECRB was transferred to the AIN. At final evaluation, which averaged 13 months postoperatively, all patients had recovered full finger and thumb flexion, scoring M4 per Medical Research Council guidelines. Average grasp strength was 5 kg, and pinch strength was 2 kg. Even in anesthetic fingers and with their eyes closed, patients could correctly identify passive extension of their distal interphalangeal joints. Wrist extension was preserved in all patients. In 4 patients, transfer of the branch of the radial nerve to the ECRB to the AIN predictably reconstructed thumb and finger flexion. Finger flexion also recovered in those fingers in which the flexor digitorum profundus was primarily innervated by the ulnar nerve. Despite extended sensory deficits, patients ultimately were able to use their hands regularly in daily life. Therapeutic III. Copyright © 2015 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.
    The Journal Of Hand Surgery 02/2015; 40(2):323-328.e2. DOI:10.1016/j.jhsa.2014.10.060 · 1.66 Impact Factor
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    ABSTRACT: The babysitter-procedure might offer an alternative when nerve reconstruction is delayed in order to overcome muscular atrophy due to denervation. In this study we aimed to show that a sensomotoric babysitter-procedure after median nerve injury is capable of preserving irreversible muscular atrophy. The median nerve of 20 female Wistar rats was denervated. 10 animals received a sensory protection with the N. cutaneous brachii. After six weeks the median nerve was reconstructed by autologous nerve grafting from the contralateral median nerve in the babysitter and the control groups. Grasping tests measured functional recovery over 15 weeks. At the end of the observation period the weight of the flexor digitorum sublimis muscle was determined. The median nerve was excised for histological examinations. Muscle weight (P < 0.0001) was significantly superior in the babysitter group compared to the control group at the end of the study. The histological evaluation revealed a significantly higher diameter of axons (P = 0.0194), nerve fiber (P = 0.0409), and nerve surface (P = 0.0184) in the babysitter group. We conclude that sensory protection of a motor nerve is capable of preserving muscule weight and we may presume that metabolism of the sensory nerve was sufficient to keep the target muscle's weight and vitality.
    BioMed Research International 07/2014; 2014:724197. DOI:10.1155/2014/724197 · 2.71 Impact Factor