Hyperemesis gravidarum and depression in pregnancy: is there an association?
ABSTRACT Objective: The aim of this study was to evaluate the impact of hyperemesis gravidarum (HG) and sociodemographic parameters on depression during pregnancy. Study design: Between September 2010 and September 2011, 200 consecutive women with HG were defined as the study group and 200 consecutive pregnant women without any signs and symptoms of HG, and matched for age, parity, and gestational age were defined as the control group. The Beck depression inventory-II (BDI-II) questionnaire and sociodemographic questionnaire evaluating educational level, occupation, economic status, and obstetric history were given to all participants for self-completion. The forms were collected within 6 h of hospital admission. Groups were compared according to the presence of depression and predictors of depression were analyzed by regression analysis. Results: Median BDI-II scores in study and control groups were 15 and 5, respectively. The difference was statistically significant (p < 0.001). In the HG group, 35.1% of patients had mild depression, 26.0% moderate, and 17.8% had severe depression, while only 5% of patients in the control group had mild depression and 95% had no depression. Multivariate analysis showed that HG, age and family relationship were related to depression during pregnancy. Moreover, depression risk was increased 76-fold in patients with HG (odds ratio = 76.000; 95% confidence interval: 36.840-156.788; p < 0.001). Conclusion: Depression risk is increased in patients with HG, therefore not only medical therapy of HG, but also psychiatric evaluation should be considered for these patients.
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ABSTRACT: Abstract The aim of this study was to compare psychological symptom of pregnants who were diagnosed with hyperemesis gravidarum and had healthy pregnancy. Research was a case-control study which included 97 first trimester pregnant women. 40 pregnant women hospitalized for hyperemesis gravidarum and 57 healthy pregnant women were included in to the study as a control group. Groups were matched in terms of age, parity and gestational age and year of marriage. Questionnaire Form and The Brief Symptom Inventory were used for collecting the data. As a result of study The Brief Symptom Inventory total score and ‘depression’, ‘anxiety’, ‘somatization’ and ‘hostility’ subscale total scores were found statistically higher than healthy pregnants (P<0.05). Pregnant women with hyperemesis gravidarum experience more problems such as depression, anxiety, somatization and hostility than healthy pregnant women. Evaluating of presence of psychological symptoms and giving suitable care while this women take nursing care to is very important both pregnant and fetus health. Keywords: Hyperemesis gravidarum; nursing care; psychological symptoms Özet Bu araştırmanın amacı Hiperemezis gravidarum tanısı alan ve sağlıklı gebelerde psikolojik semptomların karşılaştırılmasıdır. Araştırma birinci trimesterdeki 97 gebeyi içeren olgu-kontrol çalışması olarak yapılmıştır. Hiperemezis gravidarum tanısı ile hastanede yatan 40 gebe olgu ve sağlıklı 57 gebe kontrol grubu olarak araştırmaya dahil edilmiştir. Gruplar yaş, parite, gebelik haftası ve evlilik yılı açısından eşleştirilmiştir. Verilerin toplanmasında Anket Formu ve Kısa Semptom Envanteri kullanılmıştır. Araştırma sonucunda hiperemezis gravidarum grubunda Kısa Semptom Envanteri toplam puanı ve alt boyutlarından ‘depresyon’, ‘anksiyete’, ‘somatizasyon’ ve ‘hostilite’ alt boyutları toplam puanları sağlıklı gebelere göre istatistiksel anlamda yüksek saptanmıştır (P<0.05). Hiperemezis gravidarum tanısı olan gebeler sağlıklı gebelere gore daha fazla depresyon, anksiyete, somatizasyon ve hostilite sorunları yaşamaktadır. Bu gebelere bakım verirken psikolojik semptomların varlığını değerlendirmek ve uygun tedaviyi sağlamak hem gebe hem de fetüs sağlığı için oldukça önemlidir. Anahtar kelimeler: Hiperemezis gravidarum; hemşirelik bakımı; psikolojik semptomlar
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ABSTRACT: Hyperemesis gravidarum is a complex condition with a multifactorial etiology characterized by severe intractable nausea and vomiting. Despite a high prevalence, studies exploring underlying etiology and treatments are limited. We performed a literature review, focusing on articles published over the last 10 years, to examine current perspectives and recent developments in hyperemesis gravidarum.International Journal of Women's Health 08/2014; 6:719-25. DOI:10.2147/IJWH.S37685
01/2014; 20(2):1. DOI:10.5455/GMJ-30-46143