Factors associated with satisfaction with prostate cancer care: results from Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE)
ABSTRACT Study Type - Therapy (quality of care analysis) Level of Evidence 2b What's known on the subject? and What does the study add? Satisfaction with care is a comprehensive measure that incorporates structure, process, and outcome elements of individual patient's interaction with the healthcare system. Despite the worldwide public health burden of prostate cancer, little is known about predictors of satisfaction with prostate cancer care. Available data has evaluated differences in post-treatment satisfaction by treatment and demographic factors; however, few data exist regarding the contribution of both baseline and post-treatment patient-reported measures on satisfaction with care. We evaluated the relationship of various demographic, clinical, treatment, and patient-reported measures on satisfaction with care. Interestingly, while none of the evaluable demographic, clinical, or treatment parameters were associated with satisfaction, numerous patient-reported parameters were associated with satisfaction with prostate cancer care. Specifically, baseline general health-related quality of life (HRQOL) and change in prostate cancer-specific HRQOL after treatment were associated with satisfaction. Additionally, fear of cancer recurrence was also found to be associated with satisfaction. Taken together, these data may be used, in part, to identify a cohort of patients at-risk for dissatisfaction with prostate cancer care. Identification of such a group may allow for incorporation of these data into treatment counseling and/or implementing intervention strategies to improve post-treatment satisfaction. OBJECTIVE: • To evaluate the impact of demographic, clinical, treatment and patient-reported parameters on satisfaction with prostate cancer care. Despite the significant worldwide impact of prostate cancer, few data are available specifically addressing satisfaction with treatment-related care. PATIENTS AND METHODS: • CaPSURE comprises participants from 40 US sites who were monitored during and after their treatment course. • Participants who were diagnosed with clinically localized prostate cancer after 1999 underwent radical prostatectomy, radiation therapy or primary androgen deprivation, and those who also completed the satisfaction questionnaire within 2 years of treatment were included in the present study. • Satisfaction was measured using a validated instrument that assesses contact with providers, confidence in providers, communication skills, humanness and overall satisfaction. • Multivariable linear regression analysis were performed to evaluate the independent relationships between demographic, clinical, treatment and patient-reported parameters and satisfaction. RESULTS: • Of the 3056 participants, 1927 (63%) were treated with radical prostatectomy, 843 (28%) were treated with radiation therapy and 286 (9%) were treated with primary androgen deprivation. • Multivariable analysis showed that multiple patient-reported factors were independently associated with satisfaction, whereas clinical, demographic and treatment parameters were not. • Baseline health-related quality of life, measured by the 36-item short-form health survey, baseline fear of cancer recurrence (all P < 0.01) and declines in the sexual (P= 0.03), urinary (P < 0.01) and bowel (P= 0.02) function domains of the University of California Los Angeles Prostate Cancer Index were all independently associated with satisfaction. • Patient-reported outcomes were more strongly associated with satisfaction in the low-risk subgroup. CONCLUSIONS: • Patient-reported factors such as health-related quality of life and fear of cancer recurrence are independently associated with satisfaction with care • Pretreatment parameters should be used to identify populations at-risk for dissatisfaction to allow for intervention and/or incorporation into treatment decision-making.
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ABSTRACT: Purpose. Intravesical Bacillus Calmette-Guerin (BCG) immunotherapy is indicated for high-grade nonmuscle-invasive bladder cancer (NMIBC). The efficacy of BCG in patients with a history of previous pelvic radiotherapy (RT) may be diminished. We evaluated the outcomes of radical cystectomy for BCG-treated recurrent bladder cancer in patients with a history of RT for prostate cancer (PC). Methods. A retrospective chart review was performed to identify patients with primary NMIBC. We compared the outcomes of three groups of patients who underwent radical cystectomy for BCG-refractory NMIBC: those with a history of RT for PC, those who previously underwent radical prostatectomy (RP), and a cohort without PC or RT exposure. Results. From 1996 to 2008, 53 patients underwent radical cystectomy for recurrent NMIBC despite BCG. Those with previous pelvic RT were more likely to have a higher pathologic stage and decreased recurrence-free survival compared to the groups without prior RT exposure. Conclusion. Response rates for intravesical BCG therapy may be impaired in those with prior prostate radiotherapy. Patients with a history of RT who undergo radical cystectomy after failed BCG are more likely to be pathologically upstaged and have decreased recurrence-free survival. Earlier consideration of radical cystectomy may be warranted for those with NMIBC who previously received RT for PC.07/2013; 2013:405064. DOI:10.1155/2013/405064
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ABSTRACT: Patients with prostate cancer face the difficult decision between a wide range of therapeutic options. These men require elaborate information about their individual risk profile and the therapeutic strategies risks and benefits to choose the best possible option. In order to detect time trends and quality improvements between an early patient population (2003/2004) and a later reference group (2007/2008) data was analysed with regards to epidemiologic parameters, differences in diagnostics and the type and ranking of the recommended therapies taking into account changes to Gleason Grading System and implementation of new therapeutic strategies, particularly Active surveillance, in 2005. Data from all 496 consecutive patients who received consultation in 2003/2004 (n = 280) and 2007/2008 (n = 216) was retrospectively evaluated. Categorical variables were compared using the Chi-square test. Dependent variables were analysed using the unpaired Students t-test and the Mann--Whitney U-test. The cohorts were comparable concerning clinical stage, initial PSA, prostate volume, comorbidities and organ confined disease. Patients in Cohort I were younger (66.44 vs. 69.31y;p < .001) and had a longer life expectancy (17.22 vs. 14.75y;p < .001). 50.9%, 28.2% and 20.9% in Cohort I and 37.2%, 39.6% and 23.2% in Cohort II showed low-, intermediate- and high-risk disease (D Amico) with a trend towards an increased risk profile in Cohort II (p = .066). The risk-adapted therapy recommended as first option was radical prostatectomy for 91.5% in Cohort I and 69.7% in Cohort II, radiation therapy for 83.7% in Cohort I and 50.7% in Cohort II, and other therapies (brachytherapy, Active surveillance, Watchful waiting, high-intensity focused ultrasound) for 6.5% in Cohort I and 6.9% in Cohort II (p < .001). Radiation therapy was predominant in both cohorts as second treatment option (p < .001). Time trends showing quality improvement involved an increase in biopsy cores (9.95 +/- 2.38 vs. 8.43 +/- 2.29;p < .001) and an increased recommendation for bilateral nerve sparing (p < .001). In the earlier years, younger patients with a more favourable risk profile presented for interdisciplinary consultation. A unilateral recommendation for RP and EBRT was predominant. In the later years, the patient population was considerably older. However, this group may have benefitted from optimised diagnostic possibilities and a wider range of treatment options.BMC Medical Informatics and Decision Making 08/2013; 13(1):83. DOI:10.1186/1472-6947-13-83 · 1.50 Impact Factor
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ABSTRACT: Background:Prostate cancer is for many men a chronic disease with a long life expectancy after treatment. The impact of prostate cancer therapy on men has been well defined, however, explanation of the consequences of cancer treatment has not been modelled against the wider variables of long-term health-care provision. The aim of this study was to explore the parameters of unmet supportive care needs in men with prostate cancer in relation to the experience of nursing care.Methods:A survey was conducted among a volunteer sample of 1001 men with prostate cancer living in seven European countries.Results:At the time of the survey, 81% of the men had some unmet supportive care needs including psychological, sexual and health system and information needs. Logistic regression indicated that lack of post-treatment nursing care significantly predicted unmet need. Critically, men's contact with nurses and/or receipt of advice and support from nurses, for several different aspects of nursing care significantly had an impact on men's outcomes.Conclusion:Unmet need is related not only to disease and treatment factors but is also associated with the supportive care men received. Imperative to improving men's treatment outcomes is to also consider the access to nursing and the components of supportive care provided, especially after therapy.British Journal of Cancer advance online publication, 24 September 2013; doi:10.1038/bjc.2013.568 www.bjcancer.com.British Journal of Cancer 09/2013; DOI:10.1038/bjc.2013.568 · 4.82 Impact Factor