Experts question recommendations for universal lipid screenings in children

JAMA The Journal of the American Medical Association (Impact Factor: 35.29). 08/2012; 308(8):750-1. DOI: 10.1001/jama.2012.9860
Source: PubMed
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    • "Current guidelines recommend blood cholesterol screening for all children [8]. Comparison of the impact and efficiency of universal versus targeted screening programs has been rare given the limited number of universal screening programs throughout the United States for children [9] [10]. Comprehensive cardiovascular and metabolic risk detection programs designed to assess comorbidities are also rare. "
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    ABSTRACT: The Coronary Artery Risk Detection In Appalachian Communities (CARDIAC) Project has screened more than 80,000 children (10-12 years) for cardiovascular and diabetes risk factors over the past 15 years. Simultaneous referral and intervention efforts have also contributed to the overall program impact. In this study, we examined evidence of programmatic impact in the past decade at the individual, family, community, and policy levels from child screening outcomes, referral rates, participation in subsequent services, and policies that embed the activities of the project as a significant element. Within this period of time, fifth-grade overweight and obesity rates were maintained at a time when rates elsewhere increased. 107 children were referred for additional screening and treatment for probable familial hypercholesterolemia (FH); 82 family members were subsequently screened in family-based screening efforts. 58 grants were distributed throughout the state for community-appropriate obesity intervention. A state wellness policy embedded CARDIAC as the method of assessment and national child cholesterol screening guidelines were impacted by CARDIAC findings. The sustainability and successful impact of this school-based program within a largely underserved, rural Appalachian state are also discussed.
    Journal of obesity 06/2013; 2013:732579. DOI:10.1155/2013/732579
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    ABSTRACT: Childhood obesity when associated with serum lipoprotein changes triggers atherosclerosis. Evidences suggest that the atherosclerotic process begins in childhood and that the extent of early atherosclerosis of the aorta and coronary arteries can be associated with lipoprotein levels and obesity. Furthermore, many studies in childhood demonstrate an important relationship between parameters of insulin sensitivity, body fat distribution, and the development of lipid abnormalities. This review focuses on the most recent findings on the relationship between obesity, dyslipidemia, and cardiovascular risk in children.
    International Journal of Endocrinology 01/2015; 2015:1-9. DOI:10.1155/2015/912047 · 1.95 Impact Factor

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