Immune responses to resistance exercise

Human Performance Laboratory, Department of Kinesiology, University of Connecticut, Storrs, Connecticut 06269, USA.
Exercise immunology review (Impact Factor: 9.93). 01/2012; 18:8-41.
Source: PubMed

ABSTRACT Resistance exercise induces changes in leukocyte redistribution, phenotypical surface expression and leukocyte functionality. Several factors have been shown to alter the temporal pattern and/or magnitude of response including manipulation of acute program variables, the aging process, and nutritional supplementation. Rest period length and load can modify the temporal pattern and/or magnitude of leukocytosis post exercise. Aging diminishes both the duration and magnitude of the post exercise leukocytosis and reduces leukocyte functionality. The few studies that assessed the effects of nutritional supplements (e.g., carbohydrate, whey protein, caffeine) peri-resistance exercise showed minimal effects on leukocyte responses. Sex differences exist in the timing and magnitude of leukocyte infiltration into skeletal muscle. The immune response to resistance exercise is only a small part of the recovery paradigm. A better understanding of how acute program variables and other factors such as aging, sex and nutritional supplementation affect the immune response to resistance exercise is important in the context of improving recovery, performance and health.

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Available from: Daniel Freidenreich, Jul 29, 2015
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    • "We cannot ignore the fact that a decrease in lymphocytes below pre-exercise values might have been also observed in HYP, but due to our recovery window and the different durations of the exercise protocols, we were unable to observe it. Shear stress and hormonal signals have been suggested to induce the release of WBC from marginated pool (Freidenreich and Volek 2012). Elevations in cortisol are thought to lead to reductions in circulating lymphocyte counts during post-exercise recovery (Shinkai et al. 1996). "
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    Arbeitsphysiologie 08/2014; 114(12). DOI:10.1007/s00421-014-2979-6 · 2.30 Impact Factor
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    • "In general populations exercising is associated with an increase in circulating WBCs (Freidenreich and Volek 2012). Although WBCs typically return to baseline hours after an acute bout of exercise in healthy populations, it is unclear what the effect of regular exercise may be in individuals being treated for cancer whose levels are compromised as a result of adjuvant therapies. "
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    SpringerPlus 01/2014; 3:15. DOI:10.1186/2193-1801-3-15
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    • "Exercise adaptations result from a coordinated response of multiple organ systems, including cardiovascular, pulmonary, endocrine-metabolic, immunologic, and skeletal muscle, recently reviewed by Boveris and Navarro [1], by Freidenreich and Volek [2], and by Perrino et al. [3]. Exercise training has been suggested as a promising countermeasure to prevent several disease states and as a rehabilitation tool aimed to restore both muscle strength and endurance, depending on the type of exercise [4]. "
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