Depression in Parkinson's disease: Diagnosis and management

5 Boroughs Partnership NHS Foundation Trust, Warrington, UK.
British journal of hospital medicine (London, England: 2005) (Impact Factor: 0.38). 06/2012; 73(6):331-4. DOI: 10.12968/hmed.2012.73.6.331
Source: PubMed


Parkinson's disease has a high prevalence of psychiatric comorbidity including depression. This review highlights the epidemiology, aetiology and diagnosis of depression in patients with Parkinson's disease. Recommendations are made on treatment and a closer partnership between neurology and psychiatry.

7 Reads
  • Source
    • "Depressive symptoms are reported in patients with neurological pathologies (Kanner, 2012) and movement disorders (Latoo et al., 2012) but often remain underdiagnosed and undertreated. One of the chief depressive symptoms is diurnal variation that has been proposed as a predictor of the response to treatment (Wirz- Justice, 2008). "
    [Show abstract] [Hide abstract]
    ABSTRACT: Thirty patients with cerebellar ataxia and 40 healthy volunteers underwent 7 days of mood monitoring using a new device requiring a low motor load. Its convergent validity and compliance were tested. The measurements resulted consistent with validated scale scores. Patients׳ motor impairment did not affect the compliance.
    Psychiatry Research 08/2014; 220(1-2). DOI:10.1016/j.psychres.2014.07.051 · 2.47 Impact Factor
  • Source
    • "Depressive symptoms may arise after an individual suffers from a complication of a surgery or from a disease [17]. Neurological disease or injuries are known to be associated with the development of clinical depression [18]–[20]. To our knowledge, neurosensory disturbances after maxillofacial surgical procedures have not been reported as a cause of the development of depression. "
    [Show abstract] [Hide abstract]
    ABSTRACT: To investigate the effect of persistent neurosensory disturbance of the lingual nerve (LN) or inferior alveolar nerve (IAN) on life satisfaction and depression symptoms. This study recruited patients with persistent LN or IAN deficit as a consequence of lower third molar surgery for 12 months or more to form the study group. A control group was formed by matching age and gender of recruited subjects in the study group with patients without the neurosensory complications. Life satisfaction was assessed with Satisfaction With Life Scale (SWLS) and depression symptoms were assessed with 20-item Center for Epidemiological Studies Depression scale (CESD-20). Fourty-eight participants (24 cases and 24 controls) were recruited. Patients with LN or IAN deficits after lower third molar surgery were less satisfied with their lives when compared to the control group (p<0.001). They were presenting with more depression symptoms (p = 0.001). 45.8% of the study group subjects had a CESD-20 score of 16 or above. Older patients presented with more depression symptoms among the subjects with neurosensory disturbance after lower third molar surgery (p = 0.02). Individuals with permanent trigeminal neurosensory deficit after lower third molar surgery have worse life satisfaction and more depressive symptoms when compared to those who did not suffer from the surgical complication.
    PLoS ONE 08/2013; 8(8):e72891. DOI:10.1371/journal.pone.0072891 · 3.23 Impact Factor

  • Expert Opinion on Pharmacotherapy 01/2013; 14(3). DOI:10.1517/14656566.2013.759213 · 3.53 Impact Factor
Show more