Article

A Prospective Study of Weight Training and Risk of Type 2 Diabetes Mellitus in Men

Archives of internal medicine (Impact Factor: 13.25). 08/2012; 172(17):1-7. DOI: 10.1001/archinternmed.2012.3138
Source: PubMed

ABSTRACT BACKGROUND The role of weight training in the primary prevention of type 2 diabetes mellitus (T2DM) is largely unknown. METHODS To examine the association of weight training with risk of T2DM in US men and to assess the influence of combining weight training and aerobic exercise, we performed a prospective cohort study of 32 002 men from the Health Professionals Follow-up Study observed from 1990 to 2008. Weekly time spent on weight training and aerobic exercise (including brisk walking, jogging, running, bicycling, swimming, tennis, squash, and calisthenics/rowing) was obtained from questionnaires at baseline and biennially during follow-up. RESULTS During 508 332 person-years of follow-up (18 years), we documented 2278 new cases of T2DM. In multivariable-adjusted models, we observed a dose-response relationship between an increasing amount of time spent on weight training or aerobic exercise and lower risk of T2DM (P < .001 for trend). Engaging in weight training or aerobic exercise for at least 150 minutes per week was independently associated with a lower risk of T2DM of 34% (95% CI, 7%-54%) and 52% (95% CI, 45%-58%), respectively. Men who engaged in aerobic exercise and weight training for at least 150 minutes per week had the greatest reduction in T2DM risk (59%; 95% CI, 39%-73%). CONCLUSIONS Weight training was associated with a significantly lower risk of T2DM, independent of aerobic exercise. Combined weight training and aerobic exercise conferred a greater benefit.

1 Follower
 · 
124 Views
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Aims/hypothesis This study aimed to systematically review randomised controlled trials comparing the effects of aerobic exercise training (AET), resistance training (RT) and combined training (CT) on glycaemic control and blood lipids in patients with type 2 diabetes mellitus. Methods Searches were performed in MEDLINE, EMBASE and the Cochrane Library. Inclusion criteria were: type 2 diabetes mellitus, adult, supervised training and a minimum intervention period of 8 weeks. Pooled effects were calculated by fixed/random effect pairwise and Bayesian fixed/random effects network meta-analyses. Results A total of 14 trials enrolling 915 participants were included. AET was more effective than RT in improving HbA(1c) levels (mean difference [MD] -0.20% [-2.2 mmol/mol]; 95% CI -0.32, -0.08; p=0.0007, 10 trials/515 participants) and fasting glucose (MD -0.9 mmol/l; 95% CI -1.71, -0.09; p=0.03, 8 trials/245 participants). Compared with AET, CT resulted in a significantly more pronounced reduction in HbA(1c) (MD -0.17% [-1.87 mmol/mol]; 95% CI -0.31, -0.03; p=0.02, 9 trials/493 participants). Compared with RT, the MD of the change in HbA(1c) (MD -0.62%, [-6.82 mmol/mol]; 95% CI -0.95, -0.30; p=0.0002, 5 trials/362 participants], fasting glucose (MD -1.99 mmol/l; 95% CI -3.07, -0.90; p=0.0003, 3 trials/99 participants) and triacylglycerols (MD -0.28 mmol/l; 95% CI -0.46, -0.10; p=0.003, 4 trials/213 participants) were all in favour of CT. The exclusion of trials with a high risk of bias yielded only non-significant results. Conclusions/interpretation The present data suggest that CT might be the most efficacious exercise modality to improve glycaemic control and blood lipids. Interpretation with respect to clinical relevance is limited by the low quality of the studies included and the limited information on the clinically important outcomes or adverse effects of exercise.
    Diabetologia 07/2014; 57(9). DOI:10.1007/s00125-014-3303-z · 6.88 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: El presente trabajo es una revisión sistemática de la literatura específica, de los trabajos de investigación publicados en los últimos 5 años, de texto de acceso libre completo, en la base de datos de Pubmed; que contemplaran en su metodología la aplicación de ejercicios de resistencia aeróbica y de fuerza muscular, en personas con diabetes mellitus tipo 2 (DM-2). Se buscaron las palabras: diabetes type 2, resistance, aerobic, training. Luego de aplicar criterios de exclusión, quedaron 7 artículos. De los cuales se sintetizaron las características principales de los sujetos participantes; la magnitud de la carga del ejercicio: y las adaptaciones reportadas, referidas: al control de la glucemia, la composición corporal, y otras que los autores mencionaran como relevantes. El entrenamiento de fuerza y de resistencia, parecen tener similares efectos sobre la HbA1c; lo que no es igual respecto a la composición corporal, el consumo de oxígeno, y el torque muscular. Los datos presentados, dejan en claro que ambas orientaciones son relevantes para las personas con DM-2, y deben ser propuestas, en forma simultanea, desestimando el trabajo selectivo sobre una de ellas.
    3° Encuentro Nacional de Investigación e Investigadores. REDAF & IFES., Neuquén, Neuquén, Argentina; 10/2013
  • [Show abstract] [Hide abstract]
    ABSTRACT: Patients with mitochondrial cytopathies often experience exercise intolerance and may have fixed muscle weakness, leading to impaired functional capacity and lower quality of life. Endurance exercise training increases Vo 2 max, respiratory chain enzyme activity, and improves quality of life. Resistance exercise training increases muscle strength and may lower mutational burden in patients with mitochondrial DNA deletions. Both modes of exercise appear to be well tolerated. Patients with mitochondrial cytopathy should consider alternating both types of exercise to derive the benefits from each (endurance = greater aerobic fitness; resistance = greater strength). Patients should start an exercise program at a low intensity and duration, gradually increasing duration and intensity. They should "listen to their body" and not exercise on days they have fever, superimposed illness, muscle pain, or cramps, and/or if they have fasted for more than 12 hours. Children often respond best to play-based exercise and tend to enjoy intermittent activity.
    Journal of Child Neurology 07/2014; 29(9). DOI:10.1177/0883073814538512 · 1.67 Impact Factor

Full-text

Download
26 Downloads
Available from
Oct 30, 2014