Article
Magnetic resonance assessment of left ventricular volumes and mass using a single-breath-hold 3D k-t BLAST cine b-SSFP in comparison with multiple-breath-hold 2D cine b-SSFP.
Department of Radiology and Cardiology, University Hospital, Parma, Italy.
Insights into imaging
02/2011;
2(1):39-45.
DOI:10.1007/s13244-010-0056-1
Source: PubMed
- Citations (13)
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Cited In (0)
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Article: Automated segmentation of the left ventricle in cardiac MRI.
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ABSTRACT: We present a fully automated deformable model technique for myocardium segmentation in 3D MRI. Loss of signal due to blood flow, partial volume effects and significant variation of surface grey value appearance make this a difficult problem. We integrate various sources of prior knowledge learned from annotated image data into a deformable model. Inter-individual shape variation is represented by a statistical point distribution model, and the spatial relationship of the epi- and endocardium is modeled by adapting two coupled triangular surface meshes. To robustly accommodate variation of grey value appearance around the myocardiac surface, a prior parametric spatially varying feature model is established by classification of grey value surface profiles. Quantitative validation of 121 3D MRI datasets in end-diastolic (end-systolic) phase demonstrates accuracy and robustness, with 2.45 mm (2.84 mm) mean deviation from manual segmentation.Medical Image Analysis 10/2004; · 4.42 Impact Factor -
Article: Four-dimensional single breathhold magnetic resonance imaging using kt-BLAST enables reliable assessment of left- and right-ventricular volumes and mass.
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ABSTRACT: To prospectively determine the accuracy of four-dimensional (4D) kt-broad-use linear acquisition speed-up technique (BLAST) accelerated MRI (kt-BLAST) for the assessment of left-ventricular (LV) volumes and mass as well as right-ventricular (RV) volumes in comparison to standard multiple breathhold cine imaging. A total of 40 patients with suspected or known coronary artery disease (CAD) underwent cardiac MRI. In each patient a standard multislice cine steady-state free precession (SSFP) sequence was performed with complete ventricular coverage during multiple breathholds. Additionally, a kt-BLAST-accelerated 4D sequence with complete ventricular coverage was acquired during one single breathhold. For comparison of SSFP and kt-BLAST, the following LV parameters were determined: end-diastolic and end-systolic volumes, ejection fraction, end-diastolic diameter and mass. For comparison of RV dimensions, end-diastolic and end-systolic volumes and ejection fraction were assessed. LV volumes, ejection fraction, diameter, and mass showed a strong correlation between SSFP and kt-BLAST (r=0.98-0.99; P<0.01). In addition, RV parameters demonstrated a high correlation (r=0.97-0.98; P<0.01). For all parameters, the calculated bias between both methods was found to be minimal (0.4-4%). 4D kt-BLAST-accelerated MRI enabled the accurate assessment of LV and RV quantitative parameters during one single breathhold when compared to standard multislice, multiple breathhold SSFP imaging.Journal of Magnetic Resonance Imaging 04/2007; 25(4):737-42. · 2.70 Impact Factor -
Article: Fast 3D cine steady-state free precession imaging with sensitivity encoding for assessment of left ventricular function in a single breath-hold.
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ABSTRACT: This study compares single breath-hold 3D cine steady-state free precession (SSFP) MRI using sensitivity encoding (SENSE) with standard 2D cine SSFP imaging in the quantitative evaluation of global left ventricular (LV) function. The LV function of 22 healthy volunteers and 15 patients was evaluated using a standard 2D SSFP sequence and a 3D SSFP sequence with SENSE at 1.5 T. Ventricular volume, ejection fraction, and LV mass were calculated with each method, and signal-to-noise ratios (SNRs) and myocardium-to-blood contrast-to-noise ratios (CNRs) were measured. Agreement between the two methods was assessed using Bland-Altman analysis, and results were compared using a paired Student's t test (p < 0.05). The local institutional review board approved the study protocol, and all participants gave signed informed consent. The study complied with the Health Insurance Portability and Accountability Act. Both techniques produced similar estimates of ejection fraction (mean bias +/- SD, -1.2% +/- 3.6%) and LV mass (mean bias, +/- SD-1.2 +/- 10.9 g). No significant differences were found in calculated volumes, ejection fraction, or LV mass between the two methods. Acquisition time was reduced by 82%, to a single breath-hold (18 +/- 3 seconds), with the 3D SSFP technique. SNR and CNR were significantly lower with the 3D method than with the standard method. Three-dimensional SSFP imaging with SENSE can reduce acquisition time to a single breath-hold and can provide LV function quantification comparable to that obtained with conventional 2D SSFP imaging.American Journal of Roentgenology 11/2006; 187(5):1235-9. · 2.78 Impact Factor
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Keywords
2D-cine sequence
3D end-systolic volume
3D-cine sequence
46 patients
balanced steady-state free precession gradient echo
broad-use linear acquisition speed-up technique
different cardiac diseases
EF limits
excellent correlation
Functional parameters
Global functional parameters
k-t BLAST
LV EF assessment
Netherlands
patients
Philips
single-breath-hold three-dimensional cine b-SSFP
small confidence intervals
two sequences [3D end-diastolic volume
volumes
