Article

Q Fever with unusual exposure history: a classic presentation of a commonly misdiagnosed disease.

Career Epidemiology Field Officer Program, Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA.
Case reports in infectious diseases 01/2012; 2012:916142. DOI:10.1155/2012/916142
Source: PubMed

ABSTRACT We describe the case of a man presumptively diagnosed and treated for Rocky Mountain spotted fever following exposure to multiple ticks while riding horses. The laboratory testing of acute and convalescent serum specimens led to laboratory confirmation of acute Q fever as the etiology. This case represents a potential tickborne transmission of Coxiella burnetii and highlights the importance of considering Q fever as a possible diagnosis following tick exposures.

0 0
 · 
0 Bookmarks
 · 
75 Views
  • [show abstract] [hide abstract]
    ABSTRACT: Although Q fever is considered enzootic in the United States, surveillance for human Q fever has been historically limited. From 1978 through 1999, 436 cases (average = 20 per year) of human Q fever were reported. After Q fever became nationally reportable in 1999, 255 human Q fever cases (average = 51 per year) were reported with illness onset during 2000 through 2004. The median age of cases was 51 years, and most cases were male (77%). The average annual incidence of Q fever was 0.28 cases per million persons, and was highest in persons 50-59 years of age (0.39 cases per million). State-specific incidence ranged from a high of 2.40 cases per million persons in Wyoming, to 0 cases in some states. Since Q fever became reportable, case reports have increased by more than 250%. Surveillance for Q fever is essential to establish the distribution and magnitude of disease and to complement U.S. bioterrorism preparedness activities.
    The American journal of tropical medicine and hygiene 08/2006; 75(1):36-40. · 2.53 Impact Factor
  • Source
    [show abstract] [hide abstract]
    ABSTRACT: Rickettsial diseases, important causes of illness and death worldwide, exist primarily in endemic and enzootic foci that occasionally give rise to sporadic or seasonal outbreaks. Rickettsial pathogens are highly specialized for obligate intracellular survival in both the vertebrate host and the invertebrate vector. While studies often focus primarily on the vertebrate host, the arthropod vector is often more important in the natural maintenance of the pathogen. Consequently, coevolution of rickettsiae with arthropods is responsible for many features of the host-pathogen relationship that are unique among arthropod-borne diseases, including efficient pathogen replication, long-term maintenance of infection, and transstadial and transovarial transmission. This article examines the common features of the host-pathogen relationship and of the arthropod vectors of the typhus and spotted fever group rickettsiae.
    Emerging infectious diseases 01/1998; 4(2):179-86. · 5.99 Impact Factor
  • [show abstract] [hide abstract]
    ABSTRACT: Rocky Mountain spotted fever (RMSF) remains an important illness despite an effective therapy because it is difficult to diagnose and is capable of producing a fatal outcome. The pathogenesis of RMSF remains, in large part, an enigma. However, recent research has helped shed light on this mystery. Importantly, the diagnosis of RMSF must be considered in all febrile patients who have known or possible exposure to ticks, especially if they live in or have traveled to endemic regions during warmer months. Decisions about giving empiric therapy to such patients are difficult and require skill and careful judgement.
    Infectious Disease Clinics of North America 10/2008; 22(3):415-32, vii-viii. · 2.63 Impact Factor

Full-text

View
0 Downloads
Available from

Randall J Nett