Influence of Polluted SY River on Child Growth and Sex Hormones

Department of Environmental Health, School of Public Health, Zhengzhou University, Henan, China.
Biomedical and Environmental Sciences (Impact Factor: 1.65). 06/2012; 25(3):291-6. DOI: 10.3967/0895-3988.2012.03.006
Source: PubMed


To investigate the influence of the polluted SY River on children's growth and sex hormones, and provide scientific data for assessment of the polluted status of the SY River.
The study areas were selected randomly from the SY River Basin. Lead (Pb), mercury (Hg), arsenic (As), phthalates (DEP, DBP, DMP, DEHP), and bisphenol A (BPA) were measured both in the river water and in the drinking water. School children were selected by cluster sampling (n=154). Physical development indexes (height, weight, bust-circumference, and skinfold thickness) and sex hormones [testosterone (T) and estradiol (E2)] were measured for all the children.
The contents of Pb and Hg exceeded Class V standards of surface water quality in each section of the river and other indicators exceeded Class III. Compared to the control area, the concentrations of Pb, Hg, As, BPA, DEP, and DBP in the drinking water were significantly higher than in the polluted area (P<0.05). Children from the control area had significantly lower E2 and T than children from the polluted area (P<0.05). Among anthropometric results, only skinfold thickness had statistically significant difference between the two groups (P<0.05), while the other indexes showed no significant differences between the two groups (P>0.05).
The drinking water has been polluted by the SY River and affected serum sex hormone levels of children living in the polluted area.

17 Reads
  • [Show abstract] [Hide abstract]
    ABSTRACT: There is growing evidence that bisphenol A (BPA) may adversely affect humans. BPA is an endocrine disruptor that has been shown to be harmful in laboratory animal studies. Until recently, there were relatively few epidemiological studies examining the relationship between BPA and health effects in humans. However, in the last year, the number of these studies has more than doubled. A comprehensive literature search found 91 studies linking BPA to human health; 53 published within the last year. This review outlines this body of literature, showing associations between BPA exposure and adverse perinatal, childhood, and adult health outcomes, including reproductive and developmental effects, metabolic disease, and other health effects. These studies encompass both prenatal and postnatal exposures, and include several study designs and population types. While it is difficult to make causal links with epidemiological studies, the growing human literature correlating environmental BPA exposure to adverse effects in humans, along with laboratory studies in many species including primates, provides increasing support that environmental BPA exposure can be harmful to humans, especially in regards to behavioral and other effects in children.
    Reproductive Toxicology 08/2013; 42. DOI:10.1016/j.reprotox.2013.08.008 · 3.23 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The aim of this study is to evaluate the presence and concentrations of the main phthalates in water from the Jarama and Manzanares rivers in the region of Madrid (RM, Central Spain), the most densely populated region of Spain, and to determine the possible oestrogenic activity based on found phthalate concentration. The presence of phthalates in major supply drinking water areas of the RM was also analysed, thus allowing a preliminary assessment of the health risks resulting from the concentrations obtained. The results of this study show the presence of the three (dimethyl phthalate (DMP), diethyl phthalate (DEP) di-n-butyl phthalate (DBP)) of five phthalates studied (dimethyl phthalate (DMP), diethyl phthalate (DEP), di-(2-ethylhexyl) phthalate (DEHP), benzyl-butyl phthalate (BBP) and di-n-butyl phthalate (DBP)). The DBP was found in both river and tap water samplers, whereas DMP and DEP were found in only drinking water samples. The DBP was found to make the highest average contribution to pollution in both river and tap water. The DEHP was not found in both the river and tap water because it is one of the most regulated phthalates. The highest phthalate contamination was found in the Manzanares river and in those areas that receive treated water from the Tagus river. The phthalates found in river and tap water in the RM do not represent a potential oestrogenic risk for the aquatic environment or humans. A preliminary risk assessment suggested that the risk of exposure to phthalates from tap water in this study is acceptable, although continuous monitoring of the presence of these substances in both drinking and river water should be undertaken to detect possible increases in their concentrations. This is the first study to analyse the presence of phthalates in both rivers and drinking water of the centre of Spain.
    Science of The Total Environment 09/2014; 500-501C:139-146. DOI:10.1016/j.scitotenv.2014.08.098 · 4.10 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: To evaluate the distributions and health risks of phthalate esters (PAEs) in the main source water and corresponding drinking water of Zhejiang Province, the concentrations of 16 PAEs in water samples from 19 sites were measured from samples taken in the dry season and wet season. The concentration of the total PAE congeners (ΣPAEs) in source water ranged from 1.07 μg/L to 7.12 μg/L in the wet season, from 0.01 μg/L to 1.58 μg/L in the dry season, from 1.18 μg/L to 15.28 μg/L from drinking water in the wet season, and from 0.16 μg/L to 1.86 μg/L from drinking water in the dry season. Of the 16 PAEs, di-methyl phthalate (DMP), di-butyl phthalate (DBP), di-(2-ethyl-hexyl) phthalate (DEHP), di-iso-butyl phthalate (DIBP), bis-2-n-butoxyethyl phthalate (DBEP) and di-cyclohexyl phthalate (DCHP) were present in the samples analyzed, dominated by DIBP and DEHP. The concentrations of PAEs in the wet season were all relatively higher than those in the dry season, and the drinking water had higher concentrations of PAEs than source water. The PAE congeners studied pose little health risk to nearby citizens. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.
    Environmental Toxicology and Chemistry 05/2015; 34(10). DOI:10.1002/etc.3065 · 3.23 Impact Factor


17 Reads
Available from