Bariatric surgery for adolescents

Division of Pediatric and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Pediatric Diabetes (Impact Factor: 2.57). 07/2012; 14(1). DOI: 10.1111/j.1399-5448.2012.00899.x
Source: PubMed


Stefater MA, Jenkins T, Inge TH. Bariatric surgery for adolescents Pediatric Diabetes 2013: 14: 1-12. Obesity is no longer just an adult disease. An increasing number of youth are overweight, defined as body mass index (BMI) at or greater than the 95th percentile for age (1). Between 2009 and 2010, 16.9% of children aged 2-19 yr were classified as overweight based on BMI (2), as compared with only 5% of children affected by obesity in 1976-1980 (3). This is a problem of enormous proportion from a public health standpoint, as without intervention these children will grow up to become overweight and obese adults. For an obese child, the risk of becoming an obese adult may be as high as 77%, compared with 7% for a child of healthy weight (4). Morbid obesity is a major risk factor for later complications such as cardiovascular disease, type 2 diabetes, obstructive sleep apnea (OSA), polycystic ovary syndrome (PCOS), and degenerative joint disease (4-10). Obesity is also an expensive problem: the US government spends $147 billion yearly on obesity-related healthcare costs (11). Thus, there is an urgent need to target obesity in the pediatric population, before the expensive and life-threatening consequences of obesity manifest. Unfortunately, the effectiveness of medical treatments for obesity is limited. Behaviorally based dietary and physical activity interventions offer little benefit for pediatric obesity, while pharmacologic therapy is also limited and carries low success rates and recidivism (12-14) (Table 1).

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    ABSTRACT: This opinionated evidence-based selective review addresses flawed concepts related to “obesity”, bariatric surgery and approaches to treatment and prevention of a dysmetabolic syndrome of overnutrition and underactivity from the perspective of developmental origins of diseases prevalent in mid-life and beyond. Innovations focus on methods affecting appetite regulation and energy expenditure applicable throughout the life-cycle on the individual level but with transgenerational population-wide implications. Readers can expect new knowledge and enhanced understanding of a global health problem: “diabesity”.
    Maturitas 01/2013; 77(3). DOI:10.1016/j.maturitas.2013.12.004 · 2.94 Impact Factor
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    ABSTRACT: The number of obese young people continues to rise, with a corresponding increase in extreme obesity and paediatric-adolescent bariatric surgery. We aimed to (i) systematically review the literature on bariatric surgery in children and adolescents; (ii) meta-analyse change in body mass index (BMI) 1-year post-surgery and (iii) report complications, co-morbidity resolution and health-related quality of life (HRQoL). A systematic literature search (1955-2013) was performed to examine adjustable gastric band, sleeve gastrectomy, Roux-en-Y gastric bypass or biliopancreatic diversions operations among obese children and adolescents. Change in BMI a year after surgery was meta-analysed using a random effects model. In total, 637 patients from 23 studies were included in the meta-analysis. There were significant decreases in BMI at 1 year (average weighted mean BMI difference: -13.5 kg m(-2) ; 95% confidence interval [CI] -14.1 to -11.9). Complications were inconsistently reported. There was some evidence of co-morbidity resolution and improvements in HRQol post-surgery. Bariatric surgery leads to significant short-term weight loss in obese children and adolescents. However, the risks of complications are not well defined in the literature. Long-term, prospectively designed studies, with clear reporting of complications and co-morbidity resolution, alongside measures of HRQol, are needed to firmly establish the harms and benefits of bariatric surgery in children and adolescents.
    Obesity Reviews 04/2013; 14(8). DOI:10.1111/obr.12037 · 8.00 Impact Factor
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    ABSTRACT: Severe obesity is increasing in adolescents and is associated with cardiovascular disease, type 2 diabetes mellitus, obstructive sleep apnoea, polycystic ovarian syndrome and a range of musculoskeletal problems. Premature death is the inevitable outcome of persistent severe obesity in adolescents. In adults with severe obesity, medical and lifestyle interventions have been shown to be expensive and less effective in terms of weight loss than has bariatric surgery. The single completed randomised controlled trial in adolescents shows the same outcome. This is supported by meta analyses of bariatric surgery in adolescent subjects. A more aggressive approach to severe obesity, utilising bariatric surgery in selected cases, within the context of a multi-disciplinary team, is required.
    Paediatric respiratory reviews 09/2014; 15(3). DOI:10.1016/j.prrv.2014.06.001 · 2.20 Impact Factor
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