Effect of Cobalt-60 radiation on response to endodontic therapy in monkeys.

Cancer (Impact Factor: 4.89). 01/1979; 42(6):2581-90. DOI: 10.1002/1097-0142(197812)42:63.0.CO;2-3
Source: PubMed


Response of teeth that had received therapeutic doses of Cobalt-60 radiation to endodontic therapy were investigated in three monkeys. The results indicated no appreciable effect of the irradiation on the response to root canal treatment aside from reduction in osteoblastic activity.

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    ABSTRACT: Decreased sensitivity was observed in teeth within and adjacent to an irradiated field. Mandibular teeth outside the field and distal to the irradiated mandibular nerve trunk showed an immediate decrease in sensitivity, Maxillary teeth outside the field showed a delayed decrease in sensitivity. Blood flow rates and nutrition were also related to time. Neurons are though to be relatively radio-resistant and few changes were seen histologically after radiation therapy. However, functional impairment was observed in histologically normal tissue.
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