Solasodine and diosgenin: 1H and 13C assignments by two‐dimensional NMR spectroscopy

Magnetic Resonance in Chemistry (Impact Factor: 1.56). 03/1993; 31(3):278 - 282. DOI: 10.1002/mrc.1260310313

ABSTRACT Solasodine and diosgenin have been widely used as starting materials for the partial synthesis of cortisone, progresterone and C21 steroidal derivatives (oral contraceptives). This study involved the total 1H and 13C spectral assignments of these two important compounds by using two-dimensional NMR techniques (COSY, CSCM and HMBC), and resulted in unambiguous spectral assignments, especially in the convoluted regions of the spectra (1H, 0.7–2.0 ppm; 13C, 28–35 ppm).

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