Production of 13N‐labelled molecular nitrogen for pulmonary function studies
ABSTRACT A method for the production of 13NN either as a gas or as an injectable solution is described. The method is based on the 16O(p,α)13N reaction and water as target material. Following irradiation, the 13NO and 13NO are reduced to 13NH3, followed by NaOBr oxidation to 13NN. With a beam current of 1 μA and 20 min irradiation time the injectable solution contained 148 MBq (4 mCi) per ml.
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ABSTRACT: An enzymatic synthesis of13N-glutamate from13N-labeled ammonia has been developed and optimized for routine application in myocardial imaging. A remotely controlled appratus for the synthesis is described. Results of routine production runs are briefly discussed.Journal of Radioanalytical and Nuclear Chemistry 01/1991; 155(1):9-13. · 1.41 Impact Factor