Article

Catabolite repression-resistant mutants of Bacillus subtilis.

Canadian Journal of Microbiology (impact factor: 1.36). 12/1979; 25(11):1283-7. pp.1283-7
Source: PubMed

ABSTRACT Mutants of Bacillus subtilis that are able to sporulate under the condition of catabolite repression were isolated by a simple selection technique. The mutants used in the present study were able to grow normally on minimal medium with ammonium sulphate as the nitrogen source and glucose as the carbon source. Studies carried out with these mutants show that there is no close relation between catabolite repression of an inducible enzyme, acetoin dehydrogenase, and that of sporulation. Certain mutants are able to sporulate in the presence of all the carbon sources tested but some mutants are resistant only to the carbon source used in isolation. It is suggested that several metabolic steps may be affected in catabolite repression of sporulation.

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Keywords

able
 
Bacillus subtilis
 
carbon source
 
carbon sources
 
catabolite repression
 
Certain mutants
 
inducible enzyme
 
metabolic steps
 
minimal medium
 
Mutants
 
nitrogen source
 
simple selection technique
 
sporulation
 

I Takahashi