In vitro kinetics and antifungal activity of various extracts of Terminalia chebula seeds against plant pathogenic fungi
ABSTRACT The aim of the present study was to examine the efficacy of various seed extracts of Terminalia chebula as an antifungal potential against certain important plant pathogenic fungi. The organic extracts of methanol, ethyl acetate and chloroform at the used concentration of 1500 ppm/disc revealed remarkable antifungal effect as a fungal mycelial growth inhibitor against Fusarium oxysporum, Fusarium solani, Phytophthora capsici and Botrytis cinerea, in the range of 41.6–61.3%, along with MIC values ranging from 62.5 to 500 μg/ml. Also, the extracts had a strong detrimental effect on spore germination of all the tested plant pathogens along with concentration as well as time-dependent kinetic inhibition of B. cinerea. The results obtained from this study suggest that the natural products derived from Terminalia chebula could become an alternative to synthetic fungicides for controlling such important plant pathogenic fungi.
SourceAvailable from: Muhammad Sharif Mughal[Show abstract] [Hide abstract]
ABSTRACT: Over the centuries plants have ben efectively used as a potent source of traditonal medicine. Present experiment was aimed to evaluate the hypocholesterolemic and anti-atherogenic efect of feding Terminalia chebula powder (TCP) in rabits. A total of (n=20) rabits were asigned to four treatment groups with n=5 animals in each group. Experimental treatments received Normal Saline (NS); T. chebula powder (TCP), high fat diet (HFD) and high fat diet plus T. chebula powder (HFDTCP). Blod samples were taken on a wekly basis to diagnose the efects of test drug on serum Total Cholesterol (TC), LDL, HDL, Triglycerides (TG) and Atherogenic Index. Al the parameters were measured in mg/dl except the atherogenic index measured in units. In HFD rabits TC (362.59±6.0), LDL (262.59±6.12) triglycerides (258.7±2.90) and atherogenic index (13.50±1.20) was higher (p <0.05), while HDL (25.73±1.09) was significantly reduced to an alarming level at the end of eight weks. When HFD rabits were treated with TCP for eight weks, TC (132.60±4.93), LDL (89.13±2.75), Triglycerides (125.86±9.06) and atherogenic index (1.54±0.03) reduced significantly and increased (p <0.05) the HDL (52.10±1.50). It was therefore concluded thathat T. chebula powder can safely be used to reduce bad cholesterol (LDL) and to enhance god cholesterol (HDL). Key words: Medicinal plants, Terminalia chebula, HDL, LDL, Hypercholesteremia, Atherogenic IndexJournal of Animal and Plant Sciences 12/2014; 24(6):1618-1622. · 0.55 Impact Factor