Nutritional value, functional properties and nutraceutical applications of black cumin (Nigella sativa L.): An overview

International Journal of Food Science & Technology (Impact Factor: 1.38). 07/2007; 42(10):1208 - 1218. DOI: 10.1111/j.1365-2621.2006.01417.x


Non-conventional seeds are being considered because their constituents have unique chemical properties and may augment the supply of nutritional and functional products. Black cumin (Nigella sativa L.) seeds and its crude or essential oils have been widely used in traditional nutritional and medicinal applications. Consequently, black cumin has been extensively studied for its nutritional value and biological activities. The black cumin oilseed had been shown to be anticancer, antidiabetic, antiradical and immunomodulator, analgesic, antimicrobial, anti-inflammatory, spasmolytic, bronchodilator, hepatoprotective, antihypertensive and renal protective. Moreover, black seeds have many antioxidative properties and activities. In consideration of potential utilisation, detailed knowledge on the composition of black cumin oilseed is of major importance. The diversity of applications to which black cumin can be put gives this oilseed great industrial importance. This review summarises the nutritional value, functional properties and nutraceutical applications of black cumin (N. sativa L.) oilseeds.

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Available from: Mohamed Fawzy Ramadan Hassanien,
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    • "Seeds are used in the preparation of a traditional sweet dish and eaten with honey and syrup as well as for sprinkling on bread (Cheikh-Rouhou et al. 2007; Hamrouni-sellami et al. 2008). Seeds are of importance as a carminative; often they are used as a condiment in bread and other dishes (Lautenbacher 1997; Eschborn 1997; Burits and Bucar 2000; Ramadan 2007). Volatile and fixed Nigella sativa seeds oil is used worldwide for functional foods and nutraceuticals. "

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    • "NS seeds, commonly known as black seed or black cumin, and oil derived have been used for their medicinal, aromatic or flavoring properties since ancient times in different civilizations (Randhawa, 2008). The properties, composition and potential pharmacological and therapeutic activities of this species have been extensively reviewed (Salem, 2005; Ramadan, 2007; Paarakh, 2010; Ahmad et al., 2013). Studies on NS seeds and NS-derived oil have provided scientific support for their traditional use in treatment, due to their anti-diabetic activity (Bamosa et al., 2010), anticancer activity (Pichette et al., 2012), cardiovascular-protective activity (Bamosa et al., 2002), gastro-protective activity (Khaled, 2009), pulmonaryprotective and anti-asthmatic activity (Kanter, 2009) and neurological activity (Perveen et al., 2008). "
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    ABSTRACT: This review outlines the knowledge on the nutritional and zootechnical aspects of Nigella sativa (NS), which is an annual herbaceous plant native to Turkey, Pakistan and Iran. The popularity of this plant is due to its beneficial actions. NS is considered one of the most important medicinal plants in the world. Its seeds have many therapeutic effects, including antimicrobial, anticoccidial and anthelminthic activities, most of which are due to the presence of thymoquinone, which is the major bioactive component. NS seeds are also a significant source of proteins, carbohydrates and fatty acids, and thus could be added as an ingredient to formulate balance rations for farm animals. NS had positive effects on productive and reproductive performances, mortality rate, digestibility, blood chemistry parameters, milk yield and composition, compositional characteristics of eggs and carcass traits.
    Journal of Animal and Plant Sciences 08/2015; 25(4). · 0.45 Impact Factor
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    • "The seeds contain a yellowish volatile oil, a fixed oil, proteins , amino acids, reducing sugars, mucilage, alkaloids, organic acids, tannins, resins, toxic glucoside, metarbin, bitter principles, glycosidal saponins, crude fiber, minerals and vitamins (Ramadan 2007). Black cumin crude fixed seed oil is a valuable source of essential fatty acids, glycolipids, phospholipids and bioactive phytosterols (Ramadan 2007; Ramadan et al. 2012). "
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    ABSTRACT: The present study deals with investigation of larvicidal activity and their chemical constituents of the essential oil from the seeds of Nigella sativa L. (Ranunculaceae). Totally, 18 chemical compounds were identified by GC and GC-MS analysis. Thymol (19.13 %) and α-phellandrene (14.9 %) were identified as major chemical components followed by camphor (12.14 %), borneol (11.31 %), and carvacrol (8.65 %). The larval mortality was observed after 12 and 24 h of exposure period. The results revealed that the essential oil were evaluated against the fourth instar larvae of Aedes aegypti, Anopheles stephensi, and Culex quinquefasciatus. After 12 h of exposure period, the larvicidal activities were LC50 = 196.9 and LC90 = 523.5 ppm (A. aegypti), LC50 = 88.1 and LC90 = 272.4 ppm (A.stephensi), and LC50 = 241.6 and LC90 = 545.4 ppm (C. quinquefasciatus), and the larvicidal activities after 24 h of exposure period were LC50 = 99.9 and LC90 = 300.8 ppm (A. aegypti), LC50 = 53.9 and LC90 = 172.6 ppm (A. stephensi), and LC50 = 141.7 and LC90 = 364.0 ppm (C. quinquefasciatus). The results of the present study showed that the essential oil from seeds of N. sativa is inexpensive food formulation and new source of natural larvicidal agent.
    Parasitology Research 06/2015; 114(9). DOI:10.1007/s00436-015-4563-3 · 2.10 Impact Factor
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